Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy

Magnetic resonance imaging (MRI) has exquisite soft-tissue contrast and is the foundation for image guided radiotherapy (IGRT) with integrated magnetic resonance linacs. However, MRI suffers from geometrical distortions. In this study the MRI system- and patient-induced geometric distortion at four...

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Detalles Bibliográficos
Autores principales: Hasler, Signe Winther, Bernchou, Uffe, Bertelsen, Anders, van Veldhuizen, Elisabeth, Schytte, Tine, Hansen, Vibeke Nordmark, Brink, Carsten, Mahmood, Faisal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807890/
https://www.ncbi.nlm.nih.gov/pubmed/33458333
http://dx.doi.org/10.1016/j.phro.2020.07.007
Descripción
Sumario:Magnetic resonance imaging (MRI) has exquisite soft-tissue contrast and is the foundation for image guided radiotherapy (IGRT) with integrated magnetic resonance linacs. However, MRI suffers from geometrical distortions. In this study the MRI system- and patient-induced geometric distortion at four different tumor-sites was investigated: adrenal gland (7 patients), liver (4 patients), pancreas (6 patients), prostate (20 patients). Maximum level of total distortion within the gross-tumor-volume (GTV) was 0.96 mm with no significant difference between abdominal patients (adrenal gland, liver, pancreas) and pelvic patients (prostate). Total tumor-site specific distortion depended on location in the field-of-view and increased with the distance to MRI iso-center.

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