Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy

Magnetic resonance imaging (MRI) has exquisite soft-tissue contrast and is the foundation for image guided radiotherapy (IGRT) with integrated magnetic resonance linacs. However, MRI suffers from geometrical distortions. In this study the MRI system- and patient-induced geometric distortion at four...

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Autores principales: Hasler, Signe Winther, Bernchou, Uffe, Bertelsen, Anders, van Veldhuizen, Elisabeth, Schytte, Tine, Hansen, Vibeke Nordmark, Brink, Carsten, Mahmood, Faisal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807890/
https://www.ncbi.nlm.nih.gov/pubmed/33458333
http://dx.doi.org/10.1016/j.phro.2020.07.007
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author Hasler, Signe Winther
Bernchou, Uffe
Bertelsen, Anders
van Veldhuizen, Elisabeth
Schytte, Tine
Hansen, Vibeke Nordmark
Brink, Carsten
Mahmood, Faisal
author_facet Hasler, Signe Winther
Bernchou, Uffe
Bertelsen, Anders
van Veldhuizen, Elisabeth
Schytte, Tine
Hansen, Vibeke Nordmark
Brink, Carsten
Mahmood, Faisal
author_sort Hasler, Signe Winther
collection PubMed
description Magnetic resonance imaging (MRI) has exquisite soft-tissue contrast and is the foundation for image guided radiotherapy (IGRT) with integrated magnetic resonance linacs. However, MRI suffers from geometrical distortions. In this study the MRI system- and patient-induced geometric distortion at four different tumor-sites was investigated: adrenal gland (7 patients), liver (4 patients), pancreas (6 patients), prostate (20 patients). Maximum level of total distortion within the gross-tumor-volume (GTV) was 0.96 mm with no significant difference between abdominal patients (adrenal gland, liver, pancreas) and pelvic patients (prostate). Total tumor-site specific distortion depended on location in the field-of-view and increased with the distance to MRI iso-center.
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spelling pubmed-78078902021-01-14 Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy Hasler, Signe Winther Bernchou, Uffe Bertelsen, Anders van Veldhuizen, Elisabeth Schytte, Tine Hansen, Vibeke Nordmark Brink, Carsten Mahmood, Faisal Phys Imaging Radiat Oncol Original Research Article Magnetic resonance imaging (MRI) has exquisite soft-tissue contrast and is the foundation for image guided radiotherapy (IGRT) with integrated magnetic resonance linacs. However, MRI suffers from geometrical distortions. In this study the MRI system- and patient-induced geometric distortion at four different tumor-sites was investigated: adrenal gland (7 patients), liver (4 patients), pancreas (6 patients), prostate (20 patients). Maximum level of total distortion within the gross-tumor-volume (GTV) was 0.96 mm with no significant difference between abdominal patients (adrenal gland, liver, pancreas) and pelvic patients (prostate). Total tumor-site specific distortion depended on location in the field-of-view and increased with the distance to MRI iso-center. Elsevier 2020-08-19 /pmc/articles/PMC7807890/ /pubmed/33458333 http://dx.doi.org/10.1016/j.phro.2020.07.007 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research Article
Hasler, Signe Winther
Bernchou, Uffe
Bertelsen, Anders
van Veldhuizen, Elisabeth
Schytte, Tine
Hansen, Vibeke Nordmark
Brink, Carsten
Mahmood, Faisal
Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy
title Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy
title_full Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy
title_fullStr Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy
title_full_unstemmed Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy
title_short Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy
title_sort tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807890/
https://www.ncbi.nlm.nih.gov/pubmed/33458333
http://dx.doi.org/10.1016/j.phro.2020.07.007
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