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CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome

BACKGROUND: This study aimed to investigate the chest computed tomography (CT) characteristics and laboratory findings in patients with confirmed COVID-19 pneumonia and to evaluate their relationship with clinical outcome. This retrospective study assessed 164 consecutive CT chests of COVID-19 patie...

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Autores principales: Mohamed, Ibrahim A. I., Hasan, Hosam A., Abdel-Tawab, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808117/
http://dx.doi.org/10.1186/s43055-020-00385-x
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author Mohamed, Ibrahim A. I.
Hasan, Hosam A.
Abdel-Tawab, Mohamed
author_facet Mohamed, Ibrahim A. I.
Hasan, Hosam A.
Abdel-Tawab, Mohamed
author_sort Mohamed, Ibrahim A. I.
collection PubMed
description BACKGROUND: This study aimed to investigate the chest computed tomography (CT) characteristics and laboratory findings in patients with confirmed COVID-19 pneumonia and to evaluate their relationship with clinical outcome. This retrospective study assessed 164 consecutive CT chests of COVID-19 patients during April 2020. The chest CT and laboratory data were analyzed. The primary endpoint was patient survival either died or survived. The relationship between CT and laboratory findings was correlated to patient outcome. RESULTS: The study group included 164 patients (86 male, 78 women; average age, 44.3 ± 16.5 years) whose RT-PCR were positive for COVID-19. Only 120 (73.2%) patients had pulmonary manifestations. Ground glass opacities of peripheral distribution and multifocal affection were the major CT finding in COVID-19 patients. Univariate analysis revealed that CT severity score, D-dimer level, age, total leucocytic count, and absolute lymphocytic count were predictive for death. CONCLUSION: CT has an emerging role in the diagnosis of COVID-19 pneumonia and in assessing disease severity. CT severity score, D-dimer, total leucocytic count, and absolute lymphocytic count significantly predict patient survival.
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spelling pubmed-78081172021-01-15 CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome Mohamed, Ibrahim A. I. Hasan, Hosam A. Abdel-Tawab, Mohamed Egypt J Radiol Nucl Med Research BACKGROUND: This study aimed to investigate the chest computed tomography (CT) characteristics and laboratory findings in patients with confirmed COVID-19 pneumonia and to evaluate their relationship with clinical outcome. This retrospective study assessed 164 consecutive CT chests of COVID-19 patients during April 2020. The chest CT and laboratory data were analyzed. The primary endpoint was patient survival either died or survived. The relationship between CT and laboratory findings was correlated to patient outcome. RESULTS: The study group included 164 patients (86 male, 78 women; average age, 44.3 ± 16.5 years) whose RT-PCR were positive for COVID-19. Only 120 (73.2%) patients had pulmonary manifestations. Ground glass opacities of peripheral distribution and multifocal affection were the major CT finding in COVID-19 patients. Univariate analysis revealed that CT severity score, D-dimer level, age, total leucocytic count, and absolute lymphocytic count were predictive for death. CONCLUSION: CT has an emerging role in the diagnosis of COVID-19 pneumonia and in assessing disease severity. CT severity score, D-dimer, total leucocytic count, and absolute lymphocytic count significantly predict patient survival. Springer Berlin Heidelberg 2021-01-14 2021 /pmc/articles/PMC7808117/ http://dx.doi.org/10.1186/s43055-020-00385-x Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Research
Mohamed, Ibrahim A. I.
Hasan, Hosam A.
Abdel-Tawab, Mohamed
CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome
title CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome
title_full CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome
title_fullStr CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome
title_full_unstemmed CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome
title_short CT characteristics and laboratory findings of COVID-19 pneumonia in relation to patient outcome
title_sort ct characteristics and laboratory findings of covid-19 pneumonia in relation to patient outcome
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808117/
http://dx.doi.org/10.1186/s43055-020-00385-x
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