Cargando…

Antibody-mediated delivery of LIGHT to the tumor boosts natural killer cells and delays tumor progression

LIGHT is a member of the tumor necrosis factor superfamily, which has been claimed to mediate anti-tumor activity on the basis of cancer cures observed in immunocompetent mice bearing transgenic LIGHT-expressing tumors. The preclinical development of a LIGHT-based therapeutic has been hindered by th...

Descripción completa

Detalles Bibliográficos
Autores principales: Stringhini, Marco, Mock, Jacqueline, Fontana, Vanessa, Murer, Patrizia, Neri, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808322/
https://www.ncbi.nlm.nih.gov/pubmed/33404287
http://dx.doi.org/10.1080/19420862.2020.1868066

Ejemplares similares