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Sex- and cell-dependent contribution of peripheral high mobility group box 1 and TLR4 in arthritis-induced pain

Spinal high mobility group box 1 protein (HMGB1) plays crucial roles in arthritis-induced pain; however, the involvement of peripheral HMGB1 has not been examined previously. In this study, we addressed the role of peripheral HMGB1 and explored if sex contributes differentially to nociception in art...

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Detalles Bibliográficos
Autores principales: Rudjito, Resti, Agalave, Nilesh M., Farinotti, Alex Bersellini, Lundbäck, Peter, Szabo-Pardi, Thomas A., Price, Theodore J., Harris, Helena Erlandsson, Burton, Michael D., Svensson, Camilla I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808351/
https://www.ncbi.nlm.nih.gov/pubmed/32796317
http://dx.doi.org/10.1097/j.pain.0000000000002034