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Growth Factors in Oral Tissue Engineering: New Perspectives and Current Therapeutic Options

The present investigation is aimed at systematically analyzing the recent literature about the innovative scaffold involved in the reconstructive surgeries by applying growth factors and tissue engineering. An extensive review of the contemporary literature was conducted according to the PRISMA guid...

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Detalles Bibliográficos
Autores principales: Fiorillo, Luca, Cervino, Gabriele, Galindo-Moreno, Pablo, Herford, Alan Scott, Spagnuolo, Gianrico, Cicciù, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808803/
https://www.ncbi.nlm.nih.gov/pubmed/33506039
http://dx.doi.org/10.1155/2021/8840598
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author Fiorillo, Luca
Cervino, Gabriele
Galindo-Moreno, Pablo
Herford, Alan Scott
Spagnuolo, Gianrico
Cicciù, Marco
author_facet Fiorillo, Luca
Cervino, Gabriele
Galindo-Moreno, Pablo
Herford, Alan Scott
Spagnuolo, Gianrico
Cicciù, Marco
author_sort Fiorillo, Luca
collection PubMed
description The present investigation is aimed at systematically analyzing the recent literature about the innovative scaffold involved in the reconstructive surgeries by applying growth factors and tissue engineering. An extensive review of the contemporary literature was conducted according to the PRISMA guidelines by accessing the PubMed, Embase, and Scopus Elsevier databases. Authors performed the English language manuscript research published from 2003 to 2020. A total of 13 relevant studies were included in the present review. The present systematic review included only papers with significant results about correlation between scaffold, molecular features of growth factor, and reconstructive surgeries in oral maxillofacial district. The initial research with filters recorded about 1023 published papers. Beyond reading and considering of suitability, only 42 and then 36 full-text papers were recorded for the revision. All the researches recorded the possibility of using growth factors on rebuilding atrophic jaws. Different growth factors like morphogenetic factors, cytokines, and inflammatory ones and their application over different scaffold materials were recorded. Further investigations should be required in order to state scientific evidence about a clear advantage of applying tissue engineering for therapeutic purpose.
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spelling pubmed-78088032021-01-26 Growth Factors in Oral Tissue Engineering: New Perspectives and Current Therapeutic Options Fiorillo, Luca Cervino, Gabriele Galindo-Moreno, Pablo Herford, Alan Scott Spagnuolo, Gianrico Cicciù, Marco Biomed Res Int Review Article The present investigation is aimed at systematically analyzing the recent literature about the innovative scaffold involved in the reconstructive surgeries by applying growth factors and tissue engineering. An extensive review of the contemporary literature was conducted according to the PRISMA guidelines by accessing the PubMed, Embase, and Scopus Elsevier databases. Authors performed the English language manuscript research published from 2003 to 2020. A total of 13 relevant studies were included in the present review. The present systematic review included only papers with significant results about correlation between scaffold, molecular features of growth factor, and reconstructive surgeries in oral maxillofacial district. The initial research with filters recorded about 1023 published papers. Beyond reading and considering of suitability, only 42 and then 36 full-text papers were recorded for the revision. All the researches recorded the possibility of using growth factors on rebuilding atrophic jaws. Different growth factors like morphogenetic factors, cytokines, and inflammatory ones and their application over different scaffold materials were recorded. Further investigations should be required in order to state scientific evidence about a clear advantage of applying tissue engineering for therapeutic purpose. Hindawi 2021-01-06 /pmc/articles/PMC7808803/ /pubmed/33506039 http://dx.doi.org/10.1155/2021/8840598 Text en Copyright © 2021 Luca Fiorillo et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Fiorillo, Luca
Cervino, Gabriele
Galindo-Moreno, Pablo
Herford, Alan Scott
Spagnuolo, Gianrico
Cicciù, Marco
Growth Factors in Oral Tissue Engineering: New Perspectives and Current Therapeutic Options
title Growth Factors in Oral Tissue Engineering: New Perspectives and Current Therapeutic Options
title_full Growth Factors in Oral Tissue Engineering: New Perspectives and Current Therapeutic Options
title_fullStr Growth Factors in Oral Tissue Engineering: New Perspectives and Current Therapeutic Options
title_full_unstemmed Growth Factors in Oral Tissue Engineering: New Perspectives and Current Therapeutic Options
title_short Growth Factors in Oral Tissue Engineering: New Perspectives and Current Therapeutic Options
title_sort growth factors in oral tissue engineering: new perspectives and current therapeutic options
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808803/
https://www.ncbi.nlm.nih.gov/pubmed/33506039
http://dx.doi.org/10.1155/2021/8840598
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