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Kimura's Disease: A Rare Cause of Unilateral Tonsillar Enlargement

INTRODUCTION: Kimura's disease is a rare inflammatory disorder of unknown cause, commonly seen in young Asian males. Case Report. A 61-year-old male patient presented with a history of right tonsillar mass and cervical lymphadenopathy. The patient underwent hematological investigation and imagi...

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Autores principales: Khanal, Prakash, Shrestha, Agya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808821/
https://www.ncbi.nlm.nih.gov/pubmed/33505749
http://dx.doi.org/10.1155/2021/8815317
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author Khanal, Prakash
Shrestha, Agya
author_facet Khanal, Prakash
Shrestha, Agya
author_sort Khanal, Prakash
collection PubMed
description INTRODUCTION: Kimura's disease is a rare inflammatory disorder of unknown cause, commonly seen in young Asian males. Case Report. A 61-year-old male patient presented with a history of right tonsillar mass and cervical lymphadenopathy. The patient underwent hematological investigation and imaging followed by resection of tonsillar mass. Based on histopathological and subsequent immunohistochemistry reports, the case was diagnosed as Kimura's disease of the tonsil. Discussion. Kimura's disease commonly presents as painless subcutaneous masses in the head and neck region or cervical lymphadenopathy. Kimura's disease presenting as a tonsillar mass is a very rare condition. Patients usually have peripheral eosinophilia and elevated levels of serum IgE. The diagnosis is based on the clinical and histopathologic findings in a biopsy of the mass and/or lymph node along with elevated peripheral eosinophil and serum IgE level. CONCLUSION: The clinical presentation of Kimura's disease is highly variable. Kimura's disease should be considered as a differential diagnosis in patients presenting with a tonsillar mass. A high index of suspicion along with histopathological examination helps in the early diagnosis and management. Surgical excision is the treatment of choice.
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spelling pubmed-78088212021-01-26 Kimura's Disease: A Rare Cause of Unilateral Tonsillar Enlargement Khanal, Prakash Shrestha, Agya Case Rep Otolaryngol Case Report INTRODUCTION: Kimura's disease is a rare inflammatory disorder of unknown cause, commonly seen in young Asian males. Case Report. A 61-year-old male patient presented with a history of right tonsillar mass and cervical lymphadenopathy. The patient underwent hematological investigation and imaging followed by resection of tonsillar mass. Based on histopathological and subsequent immunohistochemistry reports, the case was diagnosed as Kimura's disease of the tonsil. Discussion. Kimura's disease commonly presents as painless subcutaneous masses in the head and neck region or cervical lymphadenopathy. Kimura's disease presenting as a tonsillar mass is a very rare condition. Patients usually have peripheral eosinophilia and elevated levels of serum IgE. The diagnosis is based on the clinical and histopathologic findings in a biopsy of the mass and/or lymph node along with elevated peripheral eosinophil and serum IgE level. CONCLUSION: The clinical presentation of Kimura's disease is highly variable. Kimura's disease should be considered as a differential diagnosis in patients presenting with a tonsillar mass. A high index of suspicion along with histopathological examination helps in the early diagnosis and management. Surgical excision is the treatment of choice. Hindawi 2021-01-07 /pmc/articles/PMC7808821/ /pubmed/33505749 http://dx.doi.org/10.1155/2021/8815317 Text en Copyright © 2021 Prakash Khanal and Agya Shrestha. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Khanal, Prakash
Shrestha, Agya
Kimura's Disease: A Rare Cause of Unilateral Tonsillar Enlargement
title Kimura's Disease: A Rare Cause of Unilateral Tonsillar Enlargement
title_full Kimura's Disease: A Rare Cause of Unilateral Tonsillar Enlargement
title_fullStr Kimura's Disease: A Rare Cause of Unilateral Tonsillar Enlargement
title_full_unstemmed Kimura's Disease: A Rare Cause of Unilateral Tonsillar Enlargement
title_short Kimura's Disease: A Rare Cause of Unilateral Tonsillar Enlargement
title_sort kimura's disease: a rare cause of unilateral tonsillar enlargement
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808821/
https://www.ncbi.nlm.nih.gov/pubmed/33505749
http://dx.doi.org/10.1155/2021/8815317
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