Cargando…

Clinical characteristics and outcomes of critically Ill patients with COVID-19 in Northeast Ohio: low mortality and length of stay

BACKGROUND: Published coronavirus disease 2019 (COVID-19) reports suggest higher mortality with increasing age and comorbidities. Our study describes the clinical characteristics and outcomes for all intensive care unit (ICU) patients admitted across the Cleveland Clinic enterprise, a 10-hospital he...

Descripción completa

Detalles Bibliográficos
Autores principales: Fadel, Francois Abi, Al-Jaghbeer, Mohammed, Kumar, Sany, Griffiths, Lori, Wang, Xiaofeng, Han, Xiaozhen, Burton, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Critical Care Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808847/
https://www.ncbi.nlm.nih.gov/pubmed/33040520
http://dx.doi.org/10.4266/acc.2020.00619
_version_ 1783636989368598528
author Fadel, Francois Abi
Al-Jaghbeer, Mohammed
Kumar, Sany
Griffiths, Lori
Wang, Xiaofeng
Han, Xiaozhen
Burton, Robert
author_facet Fadel, Francois Abi
Al-Jaghbeer, Mohammed
Kumar, Sany
Griffiths, Lori
Wang, Xiaofeng
Han, Xiaozhen
Burton, Robert
author_sort Fadel, Francois Abi
collection PubMed
description BACKGROUND: Published coronavirus disease 2019 (COVID-19) reports suggest higher mortality with increasing age and comorbidities. Our study describes the clinical characteristics and outcomes for all intensive care unit (ICU) patients admitted across the Cleveland Clinic enterprise, a 10-hospital health care system in Northeast Ohio, serving more than 2.7 million people. METHODS: We analyzed the quality data registry for clinical characteristics and outcomes of all COVID-19-confirmed ICU admissions. Differences in outcomes from other health care systems and published cohorts from other parts of the world were delineated. RESULTS: Across our health care system, 495 COVID-19 patients were admitted from March 15 to June 1, 2020. Mean patient age was 67.3 years, 206 (41.6%) were females, and 289 (58.4%) were males. Mean Acute Physiology Score was 45.3, and mean Acute Physiology and Chronic Health Evaluation III score was 60.5. In total, 215 patients (43.3%) were intubated for a mean duration of 9.2 days. Mean ICU and hospital length of stay were 7.4 and 13.9 days, respectively, while mean ICU and hospital mortality rates were 18.4% and 23.8%. CONCLUSIONS: Our health care system cohort is the fourth largest to be reported. Lower ICU and hospital mortality and length of stay were seen compared to most other published reports. Better preparedness and state-level control of the surge in COVID-19 infections are likely the reasons for these better outcomes. Future research is needed to further delineate differences in mortality and length of stay across health care systems and over time.
format Online
Article
Text
id pubmed-7808847
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Korean Society of Critical Care Medicine
record_format MEDLINE/PubMed
spelling pubmed-78088472021-01-26 Clinical characteristics and outcomes of critically Ill patients with COVID-19 in Northeast Ohio: low mortality and length of stay Fadel, Francois Abi Al-Jaghbeer, Mohammed Kumar, Sany Griffiths, Lori Wang, Xiaofeng Han, Xiaozhen Burton, Robert Acute Crit Care Original Article BACKGROUND: Published coronavirus disease 2019 (COVID-19) reports suggest higher mortality with increasing age and comorbidities. Our study describes the clinical characteristics and outcomes for all intensive care unit (ICU) patients admitted across the Cleveland Clinic enterprise, a 10-hospital health care system in Northeast Ohio, serving more than 2.7 million people. METHODS: We analyzed the quality data registry for clinical characteristics and outcomes of all COVID-19-confirmed ICU admissions. Differences in outcomes from other health care systems and published cohorts from other parts of the world were delineated. RESULTS: Across our health care system, 495 COVID-19 patients were admitted from March 15 to June 1, 2020. Mean patient age was 67.3 years, 206 (41.6%) were females, and 289 (58.4%) were males. Mean Acute Physiology Score was 45.3, and mean Acute Physiology and Chronic Health Evaluation III score was 60.5. In total, 215 patients (43.3%) were intubated for a mean duration of 9.2 days. Mean ICU and hospital length of stay were 7.4 and 13.9 days, respectively, while mean ICU and hospital mortality rates were 18.4% and 23.8%. CONCLUSIONS: Our health care system cohort is the fourth largest to be reported. Lower ICU and hospital mortality and length of stay were seen compared to most other published reports. Better preparedness and state-level control of the surge in COVID-19 infections are likely the reasons for these better outcomes. Future research is needed to further delineate differences in mortality and length of stay across health care systems and over time. Korean Society of Critical Care Medicine 2020-11 2020-10-12 /pmc/articles/PMC7808847/ /pubmed/33040520 http://dx.doi.org/10.4266/acc.2020.00619 Text en Copyright © 2020 The Korean Society of Critical Care Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Fadel, Francois Abi
Al-Jaghbeer, Mohammed
Kumar, Sany
Griffiths, Lori
Wang, Xiaofeng
Han, Xiaozhen
Burton, Robert
Clinical characteristics and outcomes of critically Ill patients with COVID-19 in Northeast Ohio: low mortality and length of stay
title Clinical characteristics and outcomes of critically Ill patients with COVID-19 in Northeast Ohio: low mortality and length of stay
title_full Clinical characteristics and outcomes of critically Ill patients with COVID-19 in Northeast Ohio: low mortality and length of stay
title_fullStr Clinical characteristics and outcomes of critically Ill patients with COVID-19 in Northeast Ohio: low mortality and length of stay
title_full_unstemmed Clinical characteristics and outcomes of critically Ill patients with COVID-19 in Northeast Ohio: low mortality and length of stay
title_short Clinical characteristics and outcomes of critically Ill patients with COVID-19 in Northeast Ohio: low mortality and length of stay
title_sort clinical characteristics and outcomes of critically ill patients with covid-19 in northeast ohio: low mortality and length of stay
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808847/
https://www.ncbi.nlm.nih.gov/pubmed/33040520
http://dx.doi.org/10.4266/acc.2020.00619
work_keys_str_mv AT fadelfrancoisabi clinicalcharacteristicsandoutcomesofcriticallyillpatientswithcovid19innortheastohiolowmortalityandlengthofstay
AT aljaghbeermohammed clinicalcharacteristicsandoutcomesofcriticallyillpatientswithcovid19innortheastohiolowmortalityandlengthofstay
AT kumarsany clinicalcharacteristicsandoutcomesofcriticallyillpatientswithcovid19innortheastohiolowmortalityandlengthofstay
AT griffithslori clinicalcharacteristicsandoutcomesofcriticallyillpatientswithcovid19innortheastohiolowmortalityandlengthofstay
AT wangxiaofeng clinicalcharacteristicsandoutcomesofcriticallyillpatientswithcovid19innortheastohiolowmortalityandlengthofstay
AT hanxiaozhen clinicalcharacteristicsandoutcomesofcriticallyillpatientswithcovid19innortheastohiolowmortalityandlengthofstay
AT burtonrobert clinicalcharacteristicsandoutcomesofcriticallyillpatientswithcovid19innortheastohiolowmortalityandlengthofstay