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Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study
BACKGROUND: Identifying when intubated patients are ready to be extubated remains challenging. The negative inspiratory force (NIF) is a recommended predictor of weaning success. However, little is known about the role of NIF in the weaning process for the Asian surgical intensive population, especi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Critical Care Medicine
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808855/ https://www.ncbi.nlm.nih.gov/pubmed/33423439 http://dx.doi.org/10.4266/acc.2020.00598 |
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author | Vu, Phuong Hoang Tran, Viet Duc Duong, Minh Cuong Cong, Quyet Thang Nguyen, Thu |
author_facet | Vu, Phuong Hoang Tran, Viet Duc Duong, Minh Cuong Cong, Quyet Thang Nguyen, Thu |
author_sort | Vu, Phuong Hoang |
collection | PubMed |
description | BACKGROUND: Identifying when intubated patients are ready to be extubated remains challenging. The negative inspiratory force (NIF) is a recommended predictor of weaning success. However, little is known about the role of NIF in the weaning process for the Asian surgical intensive population, especially for the Vietnamese population. Here, we aimed to investigate the cutoff threshold and predictive value of the NIF index for predicting the success of ventilator weaning in Vietnamese surgical intensive care patients. METHODS: A cross-sectional study was conducted at the Surgical Intensive Care Unit of Viet Duc Hospital from October 2016 to August 2017. A total of 64 patients aged 16–70 years undergoing ventilatory support through an orotracheal tube satisfied the criteria for readiness to begin weaning. The correlation between the NIF index with outcomes of the weaning process was analyzed. Specificity (Sp), sensitivity (Se), positive predictive value (PPV), negative predictive value (NPV), receiver operating characteristic (ROC) curve, and area under the curve (AUC) were calculated. RESULTS: The success rate of the entire weaning process was 67.2% (43/64). The median NIF values were –26.0 cm H(2)O (interquartile range [IQR], –28.0 to –25.0) in the successful weaning group and –24.0 cm H(2)O (IQR, –25.0 to –23.0) in the weaning failure group (P<0.001). According to ROC analysis, an NIF value ≤–25 cm H(2)O predicted weaning success (AUC, 0.836) with 91% Se, 62% Sp, 83% PPV, and 77% NPV. CONCLUSIONS: An NIF cutoff threshold ≤–25 cm H(2)O can be used as predictor of weaning success in Vietnamese surgical intensive care patients. |
format | Online Article Text |
id | pubmed-7808855 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Korean Society of Critical Care Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-78088552021-01-26 Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study Vu, Phuong Hoang Tran, Viet Duc Duong, Minh Cuong Cong, Quyet Thang Nguyen, Thu Acute Crit Care Original Article BACKGROUND: Identifying when intubated patients are ready to be extubated remains challenging. The negative inspiratory force (NIF) is a recommended predictor of weaning success. However, little is known about the role of NIF in the weaning process for the Asian surgical intensive population, especially for the Vietnamese population. Here, we aimed to investigate the cutoff threshold and predictive value of the NIF index for predicting the success of ventilator weaning in Vietnamese surgical intensive care patients. METHODS: A cross-sectional study was conducted at the Surgical Intensive Care Unit of Viet Duc Hospital from October 2016 to August 2017. A total of 64 patients aged 16–70 years undergoing ventilatory support through an orotracheal tube satisfied the criteria for readiness to begin weaning. The correlation between the NIF index with outcomes of the weaning process was analyzed. Specificity (Sp), sensitivity (Se), positive predictive value (PPV), negative predictive value (NPV), receiver operating characteristic (ROC) curve, and area under the curve (AUC) were calculated. RESULTS: The success rate of the entire weaning process was 67.2% (43/64). The median NIF values were –26.0 cm H(2)O (interquartile range [IQR], –28.0 to –25.0) in the successful weaning group and –24.0 cm H(2)O (IQR, –25.0 to –23.0) in the weaning failure group (P<0.001). According to ROC analysis, an NIF value ≤–25 cm H(2)O predicted weaning success (AUC, 0.836) with 91% Se, 62% Sp, 83% PPV, and 77% NPV. CONCLUSIONS: An NIF cutoff threshold ≤–25 cm H(2)O can be used as predictor of weaning success in Vietnamese surgical intensive care patients. Korean Society of Critical Care Medicine 2020-11 2020-11-30 /pmc/articles/PMC7808855/ /pubmed/33423439 http://dx.doi.org/10.4266/acc.2020.00598 Text en Copyright © 2020 The Korean Society of Critical Care Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Vu, Phuong Hoang Tran, Viet Duc Duong, Minh Cuong Cong, Quyet Thang Nguyen, Thu Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study |
title | Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study |
title_full | Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study |
title_fullStr | Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study |
title_full_unstemmed | Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study |
title_short | Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study |
title_sort | predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808855/ https://www.ncbi.nlm.nih.gov/pubmed/33423439 http://dx.doi.org/10.4266/acc.2020.00598 |
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