Cargando…

Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study

BACKGROUND: Identifying when intubated patients are ready to be extubated remains challenging. The negative inspiratory force (NIF) is a recommended predictor of weaning success. However, little is known about the role of NIF in the weaning process for the Asian surgical intensive population, especi...

Descripción completa

Detalles Bibliográficos
Autores principales: Vu, Phuong Hoang, Tran, Viet Duc, Duong, Minh Cuong, Cong, Quyet Thang, Nguyen, Thu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Critical Care Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808855/
https://www.ncbi.nlm.nih.gov/pubmed/33423439
http://dx.doi.org/10.4266/acc.2020.00598
_version_ 1783636991247646720
author Vu, Phuong Hoang
Tran, Viet Duc
Duong, Minh Cuong
Cong, Quyet Thang
Nguyen, Thu
author_facet Vu, Phuong Hoang
Tran, Viet Duc
Duong, Minh Cuong
Cong, Quyet Thang
Nguyen, Thu
author_sort Vu, Phuong Hoang
collection PubMed
description BACKGROUND: Identifying when intubated patients are ready to be extubated remains challenging. The negative inspiratory force (NIF) is a recommended predictor of weaning success. However, little is known about the role of NIF in the weaning process for the Asian surgical intensive population, especially for the Vietnamese population. Here, we aimed to investigate the cutoff threshold and predictive value of the NIF index for predicting the success of ventilator weaning in Vietnamese surgical intensive care patients. METHODS: A cross-sectional study was conducted at the Surgical Intensive Care Unit of Viet Duc Hospital from October 2016 to August 2017. A total of 64 patients aged 16–70 years undergoing ventilatory support through an orotracheal tube satisfied the criteria for readiness to begin weaning. The correlation between the NIF index with outcomes of the weaning process was analyzed. Specificity (Sp), sensitivity (Se), positive predictive value (PPV), negative predictive value (NPV), receiver operating characteristic (ROC) curve, and area under the curve (AUC) were calculated. RESULTS: The success rate of the entire weaning process was 67.2% (43/64). The median NIF values were –26.0 cm H(2)O (interquartile range [IQR], –28.0 to –25.0) in the successful weaning group and –24.0 cm H(2)O (IQR, –25.0 to –23.0) in the weaning failure group (P<0.001). According to ROC analysis, an NIF value ≤–25 cm H(2)O predicted weaning success (AUC, 0.836) with 91% Se, 62% Sp, 83% PPV, and 77% NPV. CONCLUSIONS: An NIF cutoff threshold ≤–25 cm H(2)O can be used as predictor of weaning success in Vietnamese surgical intensive care patients.
format Online
Article
Text
id pubmed-7808855
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Korean Society of Critical Care Medicine
record_format MEDLINE/PubMed
spelling pubmed-78088552021-01-26 Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study Vu, Phuong Hoang Tran, Viet Duc Duong, Minh Cuong Cong, Quyet Thang Nguyen, Thu Acute Crit Care Original Article BACKGROUND: Identifying when intubated patients are ready to be extubated remains challenging. The negative inspiratory force (NIF) is a recommended predictor of weaning success. However, little is known about the role of NIF in the weaning process for the Asian surgical intensive population, especially for the Vietnamese population. Here, we aimed to investigate the cutoff threshold and predictive value of the NIF index for predicting the success of ventilator weaning in Vietnamese surgical intensive care patients. METHODS: A cross-sectional study was conducted at the Surgical Intensive Care Unit of Viet Duc Hospital from October 2016 to August 2017. A total of 64 patients aged 16–70 years undergoing ventilatory support through an orotracheal tube satisfied the criteria for readiness to begin weaning. The correlation between the NIF index with outcomes of the weaning process was analyzed. Specificity (Sp), sensitivity (Se), positive predictive value (PPV), negative predictive value (NPV), receiver operating characteristic (ROC) curve, and area under the curve (AUC) were calculated. RESULTS: The success rate of the entire weaning process was 67.2% (43/64). The median NIF values were –26.0 cm H(2)O (interquartile range [IQR], –28.0 to –25.0) in the successful weaning group and –24.0 cm H(2)O (IQR, –25.0 to –23.0) in the weaning failure group (P<0.001). According to ROC analysis, an NIF value ≤–25 cm H(2)O predicted weaning success (AUC, 0.836) with 91% Se, 62% Sp, 83% PPV, and 77% NPV. CONCLUSIONS: An NIF cutoff threshold ≤–25 cm H(2)O can be used as predictor of weaning success in Vietnamese surgical intensive care patients. Korean Society of Critical Care Medicine 2020-11 2020-11-30 /pmc/articles/PMC7808855/ /pubmed/33423439 http://dx.doi.org/10.4266/acc.2020.00598 Text en Copyright © 2020 The Korean Society of Critical Care Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Vu, Phuong Hoang
Tran, Viet Duc
Duong, Minh Cuong
Cong, Quyet Thang
Nguyen, Thu
Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study
title Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study
title_full Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study
title_fullStr Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study
title_full_unstemmed Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study
title_short Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study
title_sort predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808855/
https://www.ncbi.nlm.nih.gov/pubmed/33423439
http://dx.doi.org/10.4266/acc.2020.00598
work_keys_str_mv AT vuphuonghoang predictivevalueofthenegativeinspiratoryforceindexasapredictorofweaningsuccessacrosssectionalstudy
AT tranvietduc predictivevalueofthenegativeinspiratoryforceindexasapredictorofweaningsuccessacrosssectionalstudy
AT duongminhcuong predictivevalueofthenegativeinspiratoryforceindexasapredictorofweaningsuccessacrosssectionalstudy
AT congquyetthang predictivevalueofthenegativeinspiratoryforceindexasapredictorofweaningsuccessacrosssectionalstudy
AT nguyenthu predictivevalueofthenegativeinspiratoryforceindexasapredictorofweaningsuccessacrosssectionalstudy