Notch and TNF-α signaling promote cytoplasmic accumulation of OLFM4 in intestinal epithelium cells and exhibit a cell protective role in the inflamed mucosa of IBD patients

Notch signaling is activated in the intestinal epithelial cells (IECs) of patients with inflammatory bowel disease (IBD), and contributes to mucosal regeneration. Our previous study indicated that TNF-α and Notch signaling may synergistically promote the expression of the intestinal stem cell (ISC)...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuno, Reiko, Ito, Go, Kawamoto, Ami, Hiraguri, Yui, Sugihara, Hady Yuki, Takeoka, Sayaka, Nagata, Sayaka, Takahashi, Junichi, Tsuchiya, Mao, Anzai, Sho, Mizutani, Tomohiro, Shimizu, Hiromichi, Yui, Shiro, Oshima, Shigeru, Tsuchiya, Kiichiro, Watanabe, Mamoru, Okamoto, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808948/
https://www.ncbi.nlm.nih.gov/pubmed/33490652
http://dx.doi.org/10.1016/j.bbrep.2020.100906

Ejemplares similares

Ejemplares similares