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Prolactin receptor-driven combined luminal and epithelial differentiation in breast cancer restricts plasticity, stemness, tumorigenesis and metastasis

Dedifferentiation increased cellular plasticity and stemness are established derivers of tumor heterogeneity, metastasis and therapeutic failure resulting in incurable cancers. Therefore, it is essential to decipher pro/forward-differentiation mechanisms in cancer that may serve as therapeutic targe...

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Detalles Bibliográficos
Autores principales: Shams, Anwar, Binothman, Najat, Boudreault, Julien, Wang, Ni, Shams, Fuad, Hamam, Dana, Tian, Jun, Moamer, Alaa, Dai, Meiou, Lebrun, Jean-Jacques, Ali, Suhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809050/
https://www.ncbi.nlm.nih.gov/pubmed/33446633
http://dx.doi.org/10.1038/s41389-020-00297-5