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Tensile strength assay comparing the resistance between two different autologous platelet concentrates (leucocyte-platelet rich fibrin versus advanced-platelet rich fibrin): a pilot study

BACKGROUND: Since the leucocyte-platelet rich fibrin (L-PRF) was published in 2001, many studies have been developed, analyzing its properties, and also verifying new possibilities to improve it. Thereby, it emerges the advanced-platelet rich fibrin (A-PRF) with a protocol that optimizes the propert...

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Autores principales: Pascoal, Martim de Almeida Nóbrega Correia, dos Santos, Nuno Bernardo Malta, Completo, António Manuel Godinho, Fernandes, Gustavo Vicentis de Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809075/
https://www.ncbi.nlm.nih.gov/pubmed/33447875
http://dx.doi.org/10.1186/s40729-020-00284-w
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author Pascoal, Martim de Almeida Nóbrega Correia
dos Santos, Nuno Bernardo Malta
Completo, António Manuel Godinho
Fernandes, Gustavo Vicentis de Oliveira
author_facet Pascoal, Martim de Almeida Nóbrega Correia
dos Santos, Nuno Bernardo Malta
Completo, António Manuel Godinho
Fernandes, Gustavo Vicentis de Oliveira
author_sort Pascoal, Martim de Almeida Nóbrega Correia
collection PubMed
description BACKGROUND: Since the leucocyte-platelet rich fibrin (L-PRF) was published in 2001, many studies have been developed, analyzing its properties, and also verifying new possibilities to improve it. Thereby, it emerges the advanced-platelet rich fibrin (A-PRF) with a protocol that optimizes the properties obtained by the L-PRF. Nonetheless, there is a gap in the literature to landmark the evolutive process concerning the mechanical properties in specific the resistance to tensile strength which consequently may influence the time for membrane degradation. Thus, this study had the goal to compare the resistance to the traction of membranes produced with the original L-PRF and A-PRF protocols, being the first to this direct comparison. FINDINGS: The harvest of blood from a healthy single person, with no history of anticoagulant usage. We performed the protocols described in the literature, within a total of 13 membranes produced for each protocol (n = 26). Afterward, the membranes were prepared and submitted to a traction test assessing the maximal and the average traction achieved for each membrane. The data were analyzed statistically using the unpaired t test. Regarding average traction, A-PRF obtained a value of 0.0288 N mm(−2) and L-PRF 0.0192 N mm(−2) (p < 0.05 using unpaired t test). For maximal traction, A-PRF obtained 0.0752 N mm(−2) and L-PRF 0.0425 N mm(−2) (p < 0.05 using unpaired t test). CONCLUSION: With this study, it was possible to conclude that indeed A-PRF has a significative higher maximal traction score and higher average traction compared to L-PRF, indicating that it had a higher resistance when two opposing forces are applied.
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spelling pubmed-78090752021-01-21 Tensile strength assay comparing the resistance between two different autologous platelet concentrates (leucocyte-platelet rich fibrin versus advanced-platelet rich fibrin): a pilot study Pascoal, Martim de Almeida Nóbrega Correia dos Santos, Nuno Bernardo Malta Completo, António Manuel Godinho Fernandes, Gustavo Vicentis de Oliveira Int J Implant Dent Technical Advances Article BACKGROUND: Since the leucocyte-platelet rich fibrin (L-PRF) was published in 2001, many studies have been developed, analyzing its properties, and also verifying new possibilities to improve it. Thereby, it emerges the advanced-platelet rich fibrin (A-PRF) with a protocol that optimizes the properties obtained by the L-PRF. Nonetheless, there is a gap in the literature to landmark the evolutive process concerning the mechanical properties in specific the resistance to tensile strength which consequently may influence the time for membrane degradation. Thus, this study had the goal to compare the resistance to the traction of membranes produced with the original L-PRF and A-PRF protocols, being the first to this direct comparison. FINDINGS: The harvest of blood from a healthy single person, with no history of anticoagulant usage. We performed the protocols described in the literature, within a total of 13 membranes produced for each protocol (n = 26). Afterward, the membranes were prepared and submitted to a traction test assessing the maximal and the average traction achieved for each membrane. The data were analyzed statistically using the unpaired t test. Regarding average traction, A-PRF obtained a value of 0.0288 N mm(−2) and L-PRF 0.0192 N mm(−2) (p < 0.05 using unpaired t test). For maximal traction, A-PRF obtained 0.0752 N mm(−2) and L-PRF 0.0425 N mm(−2) (p < 0.05 using unpaired t test). CONCLUSION: With this study, it was possible to conclude that indeed A-PRF has a significative higher maximal traction score and higher average traction compared to L-PRF, indicating that it had a higher resistance when two opposing forces are applied. Springer Berlin Heidelberg 2021-01-15 /pmc/articles/PMC7809075/ /pubmed/33447875 http://dx.doi.org/10.1186/s40729-020-00284-w Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Technical Advances Article
Pascoal, Martim de Almeida Nóbrega Correia
dos Santos, Nuno Bernardo Malta
Completo, António Manuel Godinho
Fernandes, Gustavo Vicentis de Oliveira
Tensile strength assay comparing the resistance between two different autologous platelet concentrates (leucocyte-platelet rich fibrin versus advanced-platelet rich fibrin): a pilot study
title Tensile strength assay comparing the resistance between two different autologous platelet concentrates (leucocyte-platelet rich fibrin versus advanced-platelet rich fibrin): a pilot study
title_full Tensile strength assay comparing the resistance between two different autologous platelet concentrates (leucocyte-platelet rich fibrin versus advanced-platelet rich fibrin): a pilot study
title_fullStr Tensile strength assay comparing the resistance between two different autologous platelet concentrates (leucocyte-platelet rich fibrin versus advanced-platelet rich fibrin): a pilot study
title_full_unstemmed Tensile strength assay comparing the resistance between two different autologous platelet concentrates (leucocyte-platelet rich fibrin versus advanced-platelet rich fibrin): a pilot study
title_short Tensile strength assay comparing the resistance between two different autologous platelet concentrates (leucocyte-platelet rich fibrin versus advanced-platelet rich fibrin): a pilot study
title_sort tensile strength assay comparing the resistance between two different autologous platelet concentrates (leucocyte-platelet rich fibrin versus advanced-platelet rich fibrin): a pilot study
topic Technical Advances Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809075/
https://www.ncbi.nlm.nih.gov/pubmed/33447875
http://dx.doi.org/10.1186/s40729-020-00284-w
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