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Fetal bovine serum albumin inhibits antimicrobial peptide activity and binds drug only in complex with α1-antitrypsin

Several antimicrobial peptides (AMPs) have been developed for the treatment of infections caused by antibiotic-resistant microbes, but their applications are primarily limited to topical infections because in circulation they are bound and inhibited by serum proteins. Here we have found that some AM...

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Detalles Bibliográficos
Autores principales:	Tang, Wen-Hung, Wang, Chiu-Feng, Liao, You-Di
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809101/ https://www.ncbi.nlm.nih.gov/pubmed/33446738 http://dx.doi.org/10.1038/s41598-020-80540-6

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