Increased and More Heterogeneous Gadoxetic Acid Uptake of the Liver Parenchyma after Hepatitis C Virus Eradication by Direct Antiviral Agent

We evaluated the changes of gadoxetic acid uptake of the liver parenchyma after hepatitis C virus (HCV) eradication by direct-antiviral agent (DAA) therapy. The increase rate of the liver-to-muscle signal intensity ratio, the skewness and the kurtosis were calculated in the hepatobiliary phase. Afte...

Descripción completa

Detalles Bibliográficos
Autores principales: Fujita, Nobuhiro, Nishie, Akihiro, Asayama, Yoshiki, Ishigami, Kousei, Nakayama, Tomohiro, Ushijima, Yasuhiro, Kakihara, Daisuke, Takayama, Yukihisa, Morita, Koichiro, Ishimatsu, Keisuke, Takao, Seiichiro, Yoshizumi, Tomoharu, Furusyo, Norihiro, Honda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Magnetic Resonance in Medicine 2020
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809143/
https://www.ncbi.nlm.nih.gov/pubmed/32051362
http://dx.doi.org/10.2463/mrms.tn.2019-0183
Descripción
Sumario:We evaluated the changes of gadoxetic acid uptake of the liver parenchyma after hepatitis C virus (HCV) eradication by direct-antiviral agent (DAA) therapy. The increase rate of the liver-to-muscle signal intensity ratio, the skewness and the kurtosis were calculated in the hepatobiliary phase. After sustained virological response, gadoxetic acid uptake of the liver parenchyma increased, but became heterogeneous. Our study proved that HCV eradication by DAA therapy could significantly affect gadoxetic acid uptake.

Ejemplares similares