CD117/c-kit defines a prostate CSC-like subpopulation driving progression and TKI resistance

Cancer stem-like cells (CSCs) are associated with cancer progression, metastasis, and recurrence, and may also represent a subset of circulating tumor cells (CTCs). In our prior study, CTCs in advanced prostate cancer patients were found to express CD117/c-kit in a liquid biopsy. Whether CD117 expre...

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Detalles Bibliográficos
Autores principales: Harris, Koran S., Shi, Lihong, Foster, Brittni M., Mobley, Mary E., Elliott, Phyllis L., Song, Conner J., Watabe, Kounosuke, Langefeld, Carl D., Kerr, Bethany A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809150/
https://www.ncbi.nlm.nih.gov/pubmed/33446896
http://dx.doi.org/10.1038/s41598-021-81126-6

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