Penile gangrene from calciphylaxis is salvageable with intravenous sodium thiosulfate and early total parathyroidectomy

Penile gangrene is a rare but fatal complication of calciphylaxis in end-stage renal disease (ESRD). To date, there are no guidelines on its management, and outcomes are generally poor with high mortality rate. We present a case of a diabetic patient with ESRD presenting with dry gangrene of the gla...

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Autores principales: Lei, Geraldine Yanlei, Tay, Kon Voi, Hern Qi Chong, Cheryl, Ho, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809171/
https://www.ncbi.nlm.nih.gov/pubmed/33434771
http://dx.doi.org/10.1016/j.ijscr.2020.11.085
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author Lei, Geraldine Yanlei
Tay, Kon Voi
Hern Qi Chong, Cheryl
Ho, Thomas
author_facet Lei, Geraldine Yanlei
Tay, Kon Voi
Hern Qi Chong, Cheryl
Ho, Thomas
author_sort Lei, Geraldine Yanlei
collection PubMed
description Penile gangrene is a rare but fatal complication of calciphylaxis in end-stage renal disease (ESRD). To date, there are no guidelines on its management, and outcomes are generally poor with high mortality rate. We present a case of a diabetic patient with ESRD presenting with dry gangrene of the glans penis due to calciphylaxis and successfully treated with intravenous sodium thiosulfate (STS) and early total parathyroidectomy. We further analysed existing literatures on cases that utilized STS in the treatment of penile calciphylaxis.
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spelling pubmed-78091712021-01-22 Penile gangrene from calciphylaxis is salvageable with intravenous sodium thiosulfate and early total parathyroidectomy Lei, Geraldine Yanlei Tay, Kon Voi Hern Qi Chong, Cheryl Ho, Thomas Int J Surg Case Rep Case Report Penile gangrene is a rare but fatal complication of calciphylaxis in end-stage renal disease (ESRD). To date, there are no guidelines on its management, and outcomes are generally poor with high mortality rate. We present a case of a diabetic patient with ESRD presenting with dry gangrene of the glans penis due to calciphylaxis and successfully treated with intravenous sodium thiosulfate (STS) and early total parathyroidectomy. We further analysed existing literatures on cases that utilized STS in the treatment of penile calciphylaxis. Elsevier 2020-12-29 /pmc/articles/PMC7809171/ /pubmed/33434771 http://dx.doi.org/10.1016/j.ijscr.2020.11.085 Text en © 2020 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Lei, Geraldine Yanlei
Tay, Kon Voi
Hern Qi Chong, Cheryl
Ho, Thomas
Penile gangrene from calciphylaxis is salvageable with intravenous sodium thiosulfate and early total parathyroidectomy
title Penile gangrene from calciphylaxis is salvageable with intravenous sodium thiosulfate and early total parathyroidectomy
title_full Penile gangrene from calciphylaxis is salvageable with intravenous sodium thiosulfate and early total parathyroidectomy
title_fullStr Penile gangrene from calciphylaxis is salvageable with intravenous sodium thiosulfate and early total parathyroidectomy
title_full_unstemmed Penile gangrene from calciphylaxis is salvageable with intravenous sodium thiosulfate and early total parathyroidectomy
title_short Penile gangrene from calciphylaxis is salvageable with intravenous sodium thiosulfate and early total parathyroidectomy
title_sort penile gangrene from calciphylaxis is salvageable with intravenous sodium thiosulfate and early total parathyroidectomy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809171/
https://www.ncbi.nlm.nih.gov/pubmed/33434771
http://dx.doi.org/10.1016/j.ijscr.2020.11.085
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