Recombinant antibody against Trypanosoma cruzi from patients with chronic Chagas heart disease recognizes mammalian nervous system.

BACKGROUND: To deeply understand the role of antibodies in the context of Trypanosoma cruzi infection, we decided to characterize A2R1, a parasite antibody selected from single-chain variable fragment (scFv) phage display libraries constructed from B cells of chronic Chagas heart disease patients. M...

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Detalles Bibliográficos
Autores principales: Niborski, Leticia L., Potenza, Mariana, Chirivi, Renato G.S., Simonetti, Leandro, Ossowski, Micaela S., Grippo, Vanina, May, Maria, Staquicini, Daniela I., Parodi-Talice, Adriana, Robello, Carlos, Comini, Marcelo A., Alonso, Guillermo D., Raats, Jos M.H., Gómez, Karina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809174/
https://www.ncbi.nlm.nih.gov/pubmed/33429173
http://dx.doi.org/10.1016/j.ebiom.2020.103206

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