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Extensible combinatorial CRISPR screening in mammalian cells

The CRISPR-Cas system coupled with Combinatorial Genetics En Masse (CombiGEM) enables systematic analysis of high-order genetic perturbations that are important for understanding biological processes and discovering therapeutic target combinations. Here, we present detailed steps and technical consi...

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Detalles Bibliográficos
Autores principales:	Zhou, Peng, Wan, Yuk Kei, Chan, Becky K.C., Choi, Gigi C.G., Wong, Alan S.L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809193/ https://www.ncbi.nlm.nih.gov/pubmed/33490975 http://dx.doi.org/10.1016/j.xpro.2020.100255

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