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SPECC1L-deficient primary mouse embryonic palatal mesenchyme cells show speed and directionality defects

Cleft lip and/or palate (CL/P) are common anomalies occurring in 1/800 live-births. Pathogenic SPECC1L variants have been identified in patients with CL/P, which signifies a primary role for SPECC1L in craniofacial development. Specc1l mutant mouse embryos exhibit delayed palatal shelf elevation acc...

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Detalles Bibliográficos
Autores principales:	Goering, Jeremy P., Isai, Dona G., Hall, Everett G., Wilson, Nathan R., Kosa, Edina, Wenger, Luke W., Umar, Zaid, Yousaf, Abdul, Czirok, Andras, Saadi, Irfan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809270/ https://www.ncbi.nlm.nih.gov/pubmed/33446878 http://dx.doi.org/10.1038/s41598-021-81123-9

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