Tumor necrosis factor-α small interfering RNA alveolar epithelial cell-targeting nanoparticles reduce lung injury in C57BL/6J mice with sepsis

BACKGROUND: The role of tumor necrosis factor (TNF)-α small interfering (si)RNA alveolar epithelial cell (AEC)-targeting nanoparticles in lung injury is unclear. METHODS: Sixty C57BL/6J mice with sepsis were divided into normal, control, sham, 25 mg/kg, 50 mg/kg, and 100 mg/kg siRNA AEC-targeting na...

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Detalles Bibliográficos
Autores principales: Qian, Like, Yin, Xi, Ji, Jiahao, Chen, Zhengli, Fang, He, Li, Hu, Zhu, Feng, Chang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Pre-Clinical Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809319/
https://www.ncbi.nlm.nih.gov/pubmed/33435767
http://dx.doi.org/10.1177/0300060520984652

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