Two distinct catalytic pathways for GH43 xylanolytic enzymes unveiled by X-ray and QM/MM simulations

Xylanolytic enzymes from glycoside hydrolase family 43 (GH43) are involved in the breakdown of hemicellulose, the second most abundant carbohydrate in plants. Here, we kinetically and mechanistically describe the non-reducing-end xylose-releasing exo-oligoxylanase activity and report the crystal str...

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Detalles Bibliográficos
Autores principales: Morais, Mariana A. B., Coines, Joan, Domingues, Mariane N., Pirolla, Renan A. S., Tonoli, Celisa C. C., Santos, Camila R., Correa, Jessica B. L., Gozzo, Fabio C., Rovira, Carme, Murakami, Mario T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809346/
https://www.ncbi.nlm.nih.gov/pubmed/33446650
http://dx.doi.org/10.1038/s41467-020-20620-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809346/
https://www.ncbi.nlm.nih.gov/pubmed/33446650
http://dx.doi.org/10.1038/s41467-020-20620-3

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