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Two distinct catalytic pathways for GH43 xylanolytic enzymes unveiled by X-ray and QM/MM simulations
Xylanolytic enzymes from glycoside hydrolase family 43 (GH43) are involved in the breakdown of hemicellulose, the second most abundant carbohydrate in plants. Here, we kinetically and mechanistically describe the non-reducing-end xylose-releasing exo-oligoxylanase activity and report the crystal str...
Autores principales: | Morais, Mariana A. B., Coines, Joan, Domingues, Mariane N., Pirolla, Renan A. S., Tonoli, Celisa C. C., Santos, Camila R., Correa, Jessica B. L., Gozzo, Fabio C., Rovira, Carme, Murakami, Mario T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809346/ https://www.ncbi.nlm.nih.gov/pubmed/33446650 http://dx.doi.org/10.1038/s41467-020-20620-3 |
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