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Generation and functional characterization of a single-chain variable fragment (scFv) of the anti-FGF2 3F12E7 monoclonal antibody

Single-chain variable fragments (scFvs) are small-sized artificial constructs composed of the immunoglobulin heavy and light chain variable regions connected by a peptide linker. We have previously described an anti-fibroblast growth factor 2 (FGF2) immunoglobulin G (IgG) monoclonal antibody (mAb),...

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Detalles Bibliográficos
Autores principales:	de Aguiar, Rodrigo Barbosa, da Silva, Tábata de Almeida, Costa, Bruno Andrade, Machado, Marcelo Ferreira Marcondes, Yamada, Renata Yoshiko, Braggion, Camila, Perez, Kátia Regina, Mori, Marcelo Alves Silva, Oliveira, Vitor, de Moraes, Jane Zveiter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809466/ https://www.ncbi.nlm.nih.gov/pubmed/33446839 http://dx.doi.org/10.1038/s41598-020-80746-8

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