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A case of behavioral changes in a castrated male cat due to a functional adrenocortical adenoma producing testosterone and androstenedione

CASE SUMMARY: This case report describes a 9-year-old neutered male cat with a functional adrenal tumor showing aggression toward other cats in the household, excessive meowing and urine spraying. The diagnosis was made based on the clinical signs, an enlarged right adrenal gland on ultrasound, peni...

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Autores principales: Reche Junior, Archivaldo, Ramos, Daniela, Ferreira, Mariana, da Silva, Luís Artur GP, Hirai, Yumi, Horta, Pedro V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809526/
https://www.ncbi.nlm.nih.gov/pubmed/33489305
http://dx.doi.org/10.1177/2055116920981247
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author Reche Junior, Archivaldo
Ramos, Daniela
Ferreira, Mariana
da Silva, Luís Artur GP
Hirai, Yumi
Horta, Pedro V
author_facet Reche Junior, Archivaldo
Ramos, Daniela
Ferreira, Mariana
da Silva, Luís Artur GP
Hirai, Yumi
Horta, Pedro V
author_sort Reche Junior, Archivaldo
collection PubMed
description CASE SUMMARY: This case report describes a 9-year-old neutered male cat with a functional adrenal tumor showing aggression toward other cats in the household, excessive meowing and urine spraying. The diagnosis was made based on the clinical signs, an enlarged right adrenal gland on ultrasound, penile spines and elevated sex hormones on an adrenocorticotropic hormone stimulation test. The cat was submitted to celiotomy and adrenalectomy. Histopathological examination confirmed the adrenocortical adenoma. Three months after surgery the penile spines disappeared and urine spraying, as well as excessive meowing, had greatly decreased; however, aggressive behavior took much longer to stop and required behavior therapy. RELEVANCE AND NOVEL INFORMATION: Functional adrenal tumors producing only sex hormones and behavioral changes are uncommon. The cat reported herein started showing behavioral changes before spines appeared on the penis, and structural alterations in the adrenal gland at the abdominal ultrasonography were detected. Considering all the possible implications resulting from severe behavior problems such as cat–cat aggression, from a permanent separation of the cats to relinquishment, a detailed investigation of underlying medical mechanisms in these animals is crucial from the start. Examinations may need to be repeated later in the course.
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spelling pubmed-78095262021-01-22 A case of behavioral changes in a castrated male cat due to a functional adrenocortical adenoma producing testosterone and androstenedione Reche Junior, Archivaldo Ramos, Daniela Ferreira, Mariana da Silva, Luís Artur GP Hirai, Yumi Horta, Pedro V JFMS Open Rep Case Report CASE SUMMARY: This case report describes a 9-year-old neutered male cat with a functional adrenal tumor showing aggression toward other cats in the household, excessive meowing and urine spraying. The diagnosis was made based on the clinical signs, an enlarged right adrenal gland on ultrasound, penile spines and elevated sex hormones on an adrenocorticotropic hormone stimulation test. The cat was submitted to celiotomy and adrenalectomy. Histopathological examination confirmed the adrenocortical adenoma. Three months after surgery the penile spines disappeared and urine spraying, as well as excessive meowing, had greatly decreased; however, aggressive behavior took much longer to stop and required behavior therapy. RELEVANCE AND NOVEL INFORMATION: Functional adrenal tumors producing only sex hormones and behavioral changes are uncommon. The cat reported herein started showing behavioral changes before spines appeared on the penis, and structural alterations in the adrenal gland at the abdominal ultrasonography were detected. Considering all the possible implications resulting from severe behavior problems such as cat–cat aggression, from a permanent separation of the cats to relinquishment, a detailed investigation of underlying medical mechanisms in these animals is crucial from the start. Examinations may need to be repeated later in the course. SAGE Publications 2021-01-12 /pmc/articles/PMC7809526/ /pubmed/33489305 http://dx.doi.org/10.1177/2055116920981247 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Reche Junior, Archivaldo
Ramos, Daniela
Ferreira, Mariana
da Silva, Luís Artur GP
Hirai, Yumi
Horta, Pedro V
A case of behavioral changes in a castrated male cat due to a functional adrenocortical adenoma producing testosterone and androstenedione
title A case of behavioral changes in a castrated male cat due to a functional adrenocortical adenoma producing testosterone and androstenedione
title_full A case of behavioral changes in a castrated male cat due to a functional adrenocortical adenoma producing testosterone and androstenedione
title_fullStr A case of behavioral changes in a castrated male cat due to a functional adrenocortical adenoma producing testosterone and androstenedione
title_full_unstemmed A case of behavioral changes in a castrated male cat due to a functional adrenocortical adenoma producing testosterone and androstenedione
title_short A case of behavioral changes in a castrated male cat due to a functional adrenocortical adenoma producing testosterone and androstenedione
title_sort case of behavioral changes in a castrated male cat due to a functional adrenocortical adenoma producing testosterone and androstenedione
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809526/
https://www.ncbi.nlm.nih.gov/pubmed/33489305
http://dx.doi.org/10.1177/2055116920981247
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