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Network pharmacology modeling identifies synergistic interaction of therapeutic and toxicological mechanisms for Tripterygium hypoglaucum Hutch

BACKGROUND: Tripterygium hypoglaucum Hutch (THH) both has prominent efficacy and unwarranted toxicity in the treatment of autoimmune diseases. Nevertheless, its pharmacological and toxicological profiles still remain to be elucidated. In the current study, the network pharmacology approach was appli...

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Detalles Bibliográficos
Autores principales: Zhang, Dan, Dong, Yizhu, Lv, Jintao, Zhang, Bing, Zhang, Xiaomeng, Lin, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809745/
https://www.ncbi.nlm.nih.gov/pubmed/33446184
http://dx.doi.org/10.1186/s12906-021-03210-8