BRD4 inhibition alleviates mechanical stress-induced TMJ OA-like pathological changes and attenuates TREM1-mediated inflammatory response

The aim of this paper was to investigate the protective effects of bromodomain containing 4 (BRD4) inhibition on the temporomandibular joint osteoarthritis (TMJ OA) induced by compressive mechanical stress and to explore the underlying mechanism. In vivo, a rat model of TMJ compressive loading devic...

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Detalles Bibliográficos
Autores principales: Huang, Ziwei, Yang, Ren, Zhang, Lu, Zhu, Mengjiao, Zhang, Caixia, Wen, Juan, Li, Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809762/
https://www.ncbi.nlm.nih.gov/pubmed/33446277
http://dx.doi.org/10.1186/s13148-021-01008-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809762/
https://www.ncbi.nlm.nih.gov/pubmed/33446277
http://dx.doi.org/10.1186/s13148-021-01008-6

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