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Cell softness regulates tumorigenicity and stemness of cancer cells

Identifying and sorting highly tumorigenic and metastatic tumor cells from a heterogeneous cell population is a daunting challenge. Here, we show that microfluidic devices can be used to sort marker‐based heterogeneous cancer stem cells (CSC) into mechanically stiff and soft subpopulations. The isol...

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Detalles Bibliográficos
Autores principales:	Lv, Jiadi, Liu, Yaoping, Cheng, Feiran, Li, Jiping, Zhou, Yabo, Zhang, Tianzhen, Zhou, Nannan, Li, Cong, Wang, Zhenfeng, Ma, Longfei, Liu, Mengyu, Zhu, Qiang, Liu, Xiaohan, Tang, Ke, Ma, Jingwei, Zhang, Huafeng, Xie, Jing, Fang, Yi, Zhang, Haizeng, Wang, Ning, Liu, Yuying, Huang, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809788/ https://www.ncbi.nlm.nih.gov/pubmed/33274785 http://dx.doi.org/10.15252/embj.2020106123

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