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Genipin and insulin combined treatment improves implant osseointegration in type 2 diabetic rats
BACKGROUND: Type 2 diabetes mellitus (T2DM) has a harmful effect on the stability and osseointegration of dental implants. T2DM induces mitochondrial damage by inhibiting AMPK signaling, resulting in oxidative stress and poor osteogenesis in the peri-implant bone area. Genipin is a major component o...
Autores principales: | Zhang, Jiajia, Wang, Ya-nan, Jia, Tingting, Huang, Haiyun, Zhang, Dongjiao, Xu, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809857/ https://www.ncbi.nlm.nih.gov/pubmed/33446235 http://dx.doi.org/10.1186/s13018-021-02210-1 |
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