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Cross-talks among GBA mutations, glucocerebrosidase, and α-synuclein in GBA-associated Parkinson’s disease and their targeted therapeutic approaches: a comprehensive review

Current therapies for Parkinson’s disease (PD) are palliative, of which the levodopa/carbidopa therapy remains the primary choice but is unable to modulate the progression of neurodegeneration. Due to the complication of such a multifactorial disorder and significant limitations of the therapy, nume...

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Detalles Bibliográficos
Autores principales: Behl, Tapan, Kaur, Gagandeep, Fratila, Ovidiu, Buhas, Camelia, Judea-Pusta, Claudia Teodora, Negrut, Nicoleta, Bustea, Cristiana, Bungau, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809876/
https://www.ncbi.nlm.nih.gov/pubmed/33446243
http://dx.doi.org/10.1186/s40035-020-00226-x