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Nogo-66 promotes β-amyloid protein secretion via NgR/ROCK-dependent BACE1 activation

The generation of β-amyloid protein (Aβ) is considered a key step in the pathogenesis of Alzheimer's disease (AD) and the regulation of its production is an important therapeutic strategy. It was hypothesized in the present study that Nogo-A may be involved in AD and may regulate the generation...

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Detalles Bibliográficos
Autores principales:	Xie, Qing-Qing, Feng, Xiao, Huang, Yi-Yun, Fang, Nian, Yi, Hua, Wang, Zi-Jian, Cao, Qiao-Yu, Lou, Guo-Feng, Pan, Jun-Ping, Hu, Yang, Li, Fang-Cheng, Zheng, Qing, Xiao, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809900/ https://www.ncbi.nlm.nih.gov/pubmed/33495810 http://dx.doi.org/10.3892/mmr.2021.11827

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