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Programmable Gene Knockdown in Diverse Bacteria Using Mobile‐CRISPRi

Facile bacterial genome sequencing has unlocked a veritable treasure trove of novel genes awaiting functional exploration. To make the most of this opportunity requires powerful genetic tools that can target all genes in diverse bacteria. CRISPR interference (CRISPRi) is a programmable gene‐knockdow...

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Detalles Bibliográficos
Autores principales: Banta, Amy B., Ward, Ryan D., Tran, Jennifer S., Bacon, Emily E., Peters, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809906/
https://www.ncbi.nlm.nih.gov/pubmed/33332762
http://dx.doi.org/10.1002/cpmc.130