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Clinico-Etiological Evaluation of Chronic Leg Ulcer in a Tertiary Care Center of Eastern India

BACKGROUND: A chronic leg ulcer (CLU) is a significant public health problem. It has various etiologies. Racial, familial, occupational, and social factors may also have an impact on the prevalence of different causes of leg ulcers. Though there are western data on the epidemiology of leg ulcer, sim...

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Autores principales: Nag, Falguni, Chatterjee, Gobinda, Ghosh, Arghyaprasun, De, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810075/
https://www.ncbi.nlm.nih.gov/pubmed/33487705
http://dx.doi.org/10.4103/ijd.IJD_62_20
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author Nag, Falguni
Chatterjee, Gobinda
Ghosh, Arghyaprasun
De, Abhishek
author_facet Nag, Falguni
Chatterjee, Gobinda
Ghosh, Arghyaprasun
De, Abhishek
author_sort Nag, Falguni
collection PubMed
description BACKGROUND: A chronic leg ulcer (CLU) is a significant public health problem. It has various etiologies. Racial, familial, occupational, and social factors may also have an impact on the prevalence of different causes of leg ulcers. Though there are western data on the epidemiology of leg ulcer, similar data are largely unavailable from our part of the world. AIMS: We undertook a study in a tertiary care center in eastern India to determine the clinical and etiological pattern of patients with CLU. MATERIALS AND METHODS: Hundred consecutive patients presenting with CLU, fulfilling the criteria, were included after informed consent. Patients were subjected to proper history taking, clinical examination, routine blood test, and pus for culture and sensitivity test (where needed) along with Ankle Brachial Index (ABI). RESULTS: Among the 100 patients, venous ulcer (34%) was predominant followed by arterial ulcer (14%), mixed arterial and venous ulcer (11%). History of smoking (56%) and obesity (BMI >25) (32%) were the common risk factors in leg ulcer patients. Fifty nine percent of the total CLU were infected and out of this, 86.4% showed growth of microorganisms. Staphylococcus aureus (39%) was the most commonly isolated organism, followed by Pseudomonas aeruginosa (15%). Eleven (24.44%) clinically diagnosed venous ulcer patients showed significantly lower ABI (<0.9) and were diagnosed as mixed ulcer (a venous ulcer with a peripheral arterial disease). CONCLUSION: Venous ulcer and mixed ulcer are the most common type of CLU.
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spelling pubmed-78100752021-01-22 Clinico-Etiological Evaluation of Chronic Leg Ulcer in a Tertiary Care Center of Eastern India Nag, Falguni Chatterjee, Gobinda Ghosh, Arghyaprasun De, Abhishek Indian J Dermatol Original Article BACKGROUND: A chronic leg ulcer (CLU) is a significant public health problem. It has various etiologies. Racial, familial, occupational, and social factors may also have an impact on the prevalence of different causes of leg ulcers. Though there are western data on the epidemiology of leg ulcer, similar data are largely unavailable from our part of the world. AIMS: We undertook a study in a tertiary care center in eastern India to determine the clinical and etiological pattern of patients with CLU. MATERIALS AND METHODS: Hundred consecutive patients presenting with CLU, fulfilling the criteria, were included after informed consent. Patients were subjected to proper history taking, clinical examination, routine blood test, and pus for culture and sensitivity test (where needed) along with Ankle Brachial Index (ABI). RESULTS: Among the 100 patients, venous ulcer (34%) was predominant followed by arterial ulcer (14%), mixed arterial and venous ulcer (11%). History of smoking (56%) and obesity (BMI >25) (32%) were the common risk factors in leg ulcer patients. Fifty nine percent of the total CLU were infected and out of this, 86.4% showed growth of microorganisms. Staphylococcus aureus (39%) was the most commonly isolated organism, followed by Pseudomonas aeruginosa (15%). Eleven (24.44%) clinically diagnosed venous ulcer patients showed significantly lower ABI (<0.9) and were diagnosed as mixed ulcer (a venous ulcer with a peripheral arterial disease). CONCLUSION: Venous ulcer and mixed ulcer are the most common type of CLU. Wolters Kluwer - Medknow 2020 /pmc/articles/PMC7810075/ /pubmed/33487705 http://dx.doi.org/10.4103/ijd.IJD_62_20 Text en Copyright: © 2020 Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Nag, Falguni
Chatterjee, Gobinda
Ghosh, Arghyaprasun
De, Abhishek
Clinico-Etiological Evaluation of Chronic Leg Ulcer in a Tertiary Care Center of Eastern India
title Clinico-Etiological Evaluation of Chronic Leg Ulcer in a Tertiary Care Center of Eastern India
title_full Clinico-Etiological Evaluation of Chronic Leg Ulcer in a Tertiary Care Center of Eastern India
title_fullStr Clinico-Etiological Evaluation of Chronic Leg Ulcer in a Tertiary Care Center of Eastern India
title_full_unstemmed Clinico-Etiological Evaluation of Chronic Leg Ulcer in a Tertiary Care Center of Eastern India
title_short Clinico-Etiological Evaluation of Chronic Leg Ulcer in a Tertiary Care Center of Eastern India
title_sort clinico-etiological evaluation of chronic leg ulcer in a tertiary care center of eastern india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810075/
https://www.ncbi.nlm.nih.gov/pubmed/33487705
http://dx.doi.org/10.4103/ijd.IJD_62_20
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