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A Case of Methyl Ethyl Ketone Peroxide Ingestion Complicated by Rhabdomyolysis

Methyl ethyl ketone peroxide (MEKP) is a colorless-to-faintly-yellow liquid that is used as a cross-linking to harden plastics or resins in various industries. It is also an ingredient of paints, varnishes, and paint removers. Because of the high reactivity of MEKP, it is available only as a 40% to...

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Autores principales: Dhir, Abhishek, Kaur, Baldeep, Syal, Arshi, Gupta, Monica, Mehdi, Zainab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810179/
https://www.ncbi.nlm.nih.gov/pubmed/33489533
http://dx.doi.org/10.7759/cureus.12119
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author Dhir, Abhishek
Kaur, Baldeep
Syal, Arshi
Gupta, Monica
Mehdi, Zainab
author_facet Dhir, Abhishek
Kaur, Baldeep
Syal, Arshi
Gupta, Monica
Mehdi, Zainab
author_sort Dhir, Abhishek
collection PubMed
description Methyl ethyl ketone peroxide (MEKP) is a colorless-to-faintly-yellow liquid that is used as a cross-linking to harden plastics or resins in various industries. It is also an ingredient of paints, varnishes, and paint removers. Because of the high reactivity of MEKP, it is available only as a 40% to 60% solution in dimethyl phthalate or other phthalates. Post-ingestion, the spectrum of complications is vast, ranging from corrosive injury in the oral cavity and gastrointestinal tract to fulminant hepatic toxicity, sepsis, multi-organ failure, and disseminated intravascular coagulation. We report the case of a 40-year-old, self-employed, male worker in a lamination workshop, who presented with accidental ingestion of MEKP from an unlabeled container. He subsequently developed a multitude of complications, most noteworthy being rhabdomyolysis and in turn acute kidney injury. The patient was managed in the intensive care unit with supportive management and hemodialysis sessions; however, the patient succumbed to his illness, despite aggressive measures.
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spelling pubmed-78101792021-01-22 A Case of Methyl Ethyl Ketone Peroxide Ingestion Complicated by Rhabdomyolysis Dhir, Abhishek Kaur, Baldeep Syal, Arshi Gupta, Monica Mehdi, Zainab Cureus Emergency Medicine Methyl ethyl ketone peroxide (MEKP) is a colorless-to-faintly-yellow liquid that is used as a cross-linking to harden plastics or resins in various industries. It is also an ingredient of paints, varnishes, and paint removers. Because of the high reactivity of MEKP, it is available only as a 40% to 60% solution in dimethyl phthalate or other phthalates. Post-ingestion, the spectrum of complications is vast, ranging from corrosive injury in the oral cavity and gastrointestinal tract to fulminant hepatic toxicity, sepsis, multi-organ failure, and disseminated intravascular coagulation. We report the case of a 40-year-old, self-employed, male worker in a lamination workshop, who presented with accidental ingestion of MEKP from an unlabeled container. He subsequently developed a multitude of complications, most noteworthy being rhabdomyolysis and in turn acute kidney injury. The patient was managed in the intensive care unit with supportive management and hemodialysis sessions; however, the patient succumbed to his illness, despite aggressive measures. Cureus 2020-12-17 /pmc/articles/PMC7810179/ /pubmed/33489533 http://dx.doi.org/10.7759/cureus.12119 Text en Copyright © 2020, Dhir et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Dhir, Abhishek
Kaur, Baldeep
Syal, Arshi
Gupta, Monica
Mehdi, Zainab
A Case of Methyl Ethyl Ketone Peroxide Ingestion Complicated by Rhabdomyolysis
title A Case of Methyl Ethyl Ketone Peroxide Ingestion Complicated by Rhabdomyolysis
title_full A Case of Methyl Ethyl Ketone Peroxide Ingestion Complicated by Rhabdomyolysis
title_fullStr A Case of Methyl Ethyl Ketone Peroxide Ingestion Complicated by Rhabdomyolysis
title_full_unstemmed A Case of Methyl Ethyl Ketone Peroxide Ingestion Complicated by Rhabdomyolysis
title_short A Case of Methyl Ethyl Ketone Peroxide Ingestion Complicated by Rhabdomyolysis
title_sort case of methyl ethyl ketone peroxide ingestion complicated by rhabdomyolysis
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810179/
https://www.ncbi.nlm.nih.gov/pubmed/33489533
http://dx.doi.org/10.7759/cureus.12119
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