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Palmitate induces fat accumulation via repressing FoxO1-mediated ATGL-dependent lipolysis in HepG2 hepatocytes
Obesity is closely associated with non-alcoholic fatty liver disease (NAFLD), and elevated serum palmitate is the link between obesity and excessive hepatic lipid accumulation. Forkhead box O-1 (FoxO1) is one of the FoxO family members of transcription factors and can stimulate adipose triglyceride...
Autores principales: | Zhao, Naiqian, Tan, Huiwen, Wang, Li, Han, Le, Cheng, Yanli, Feng, Ying, Li, Ting, Liu, Xiaoling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810308/ https://www.ncbi.nlm.nih.gov/pubmed/33449950 http://dx.doi.org/10.1371/journal.pone.0243938 |
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