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The translocon-associated protein (TRAP) complex regulates quality control of N-linked glycosylation during ER stress
Asparagine (N)–linked glycosylation is required for endoplasmic reticulum (ER) homeostasis, but how this co- and posttranslational modification is maintained during ER stress is unknown. Here, we introduce a fluorescence-based strategy to detect aberrant N-glycosylation in individual cells and ident...
Autores principales: | Phoomak, Chatchai, Cui, Wei, Hayman, Thomas J., Yu, Seok-Ho, Zhao, Peng, Wells, Lance, Steet, Richard, Contessa, Joseph N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810369/ https://www.ncbi.nlm.nih.gov/pubmed/33523898 http://dx.doi.org/10.1126/sciadv.abc6364 |
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