Cargando…

Outcomes of fertility investigations in a cohort of adults with perinatally acquired HIV-1 infection: a UK cross-sectional observational study

There are no published studies of fertility measurements in people living with perinatally acquired HIV (PaHIV). We performed fertility investigations in 25 adults with PaHIV. Seven (78%) men had sperm morphology normal forms (%) below the fifth centile for the general population with four (44%) hav...

Descripción completa

Detalles Bibliográficos
Autores principales: Pasvol, Thomas J., Teh, Jhia, Balfoussia, Danai, Hall, Rebecca, Petersen, Claire, Khan, Maryam, Ayres, Sara, Jayasena, Channa N., Foster, Caroline, Fidler, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810410/
https://www.ncbi.nlm.nih.gov/pubmed/33165031
http://dx.doi.org/10.1097/QAD.0000000000002745
_version_ 1783637308024553472
author Pasvol, Thomas J.
Teh, Jhia
Balfoussia, Danai
Hall, Rebecca
Petersen, Claire
Khan, Maryam
Ayres, Sara
Jayasena, Channa N.
Foster, Caroline
Fidler, Sarah
author_facet Pasvol, Thomas J.
Teh, Jhia
Balfoussia, Danai
Hall, Rebecca
Petersen, Claire
Khan, Maryam
Ayres, Sara
Jayasena, Channa N.
Foster, Caroline
Fidler, Sarah
author_sort Pasvol, Thomas J.
collection PubMed
description There are no published studies of fertility measurements in people living with perinatally acquired HIV (PaHIV). We performed fertility investigations in 25 adults with PaHIV. Seven (78%) men had sperm morphology normal forms (%) below the fifth centile for the general population with four (44%) having no normal forms. Mean (SD) serum anti-Müllerian hormone level was 19.4 (9.5) pmol/l; lower than expected for this age group. A larger study is needed to verify our findings.
format Online
Article
Text
id pubmed-7810410
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-78104102021-02-01 Outcomes of fertility investigations in a cohort of adults with perinatally acquired HIV-1 infection: a UK cross-sectional observational study Pasvol, Thomas J. Teh, Jhia Balfoussia, Danai Hall, Rebecca Petersen, Claire Khan, Maryam Ayres, Sara Jayasena, Channa N. Foster, Caroline Fidler, Sarah AIDS Research Letter There are no published studies of fertility measurements in people living with perinatally acquired HIV (PaHIV). We performed fertility investigations in 25 adults with PaHIV. Seven (78%) men had sperm morphology normal forms (%) below the fifth centile for the general population with four (44%) having no normal forms. Mean (SD) serum anti-Müllerian hormone level was 19.4 (9.5) pmol/l; lower than expected for this age group. A larger study is needed to verify our findings. Lippincott Williams & Wilkins 2021-02-02 2021-11-05 /pmc/articles/PMC7810410/ /pubmed/33165031 http://dx.doi.org/10.1097/QAD.0000000000002745 Text en Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle Research Letter
Pasvol, Thomas J.
Teh, Jhia
Balfoussia, Danai
Hall, Rebecca
Petersen, Claire
Khan, Maryam
Ayres, Sara
Jayasena, Channa N.
Foster, Caroline
Fidler, Sarah
Outcomes of fertility investigations in a cohort of adults with perinatally acquired HIV-1 infection: a UK cross-sectional observational study
title Outcomes of fertility investigations in a cohort of adults with perinatally acquired HIV-1 infection: a UK cross-sectional observational study
title_full Outcomes of fertility investigations in a cohort of adults with perinatally acquired HIV-1 infection: a UK cross-sectional observational study
title_fullStr Outcomes of fertility investigations in a cohort of adults with perinatally acquired HIV-1 infection: a UK cross-sectional observational study
title_full_unstemmed Outcomes of fertility investigations in a cohort of adults with perinatally acquired HIV-1 infection: a UK cross-sectional observational study
title_short Outcomes of fertility investigations in a cohort of adults with perinatally acquired HIV-1 infection: a UK cross-sectional observational study
title_sort outcomes of fertility investigations in a cohort of adults with perinatally acquired hiv-1 infection: a uk cross-sectional observational study
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810410/
https://www.ncbi.nlm.nih.gov/pubmed/33165031
http://dx.doi.org/10.1097/QAD.0000000000002745
work_keys_str_mv AT pasvolthomasj outcomesoffertilityinvestigationsinacohortofadultswithperinatallyacquiredhiv1infectionaukcrosssectionalobservationalstudy
AT tehjhia outcomesoffertilityinvestigationsinacohortofadultswithperinatallyacquiredhiv1infectionaukcrosssectionalobservationalstudy
AT balfoussiadanai outcomesoffertilityinvestigationsinacohortofadultswithperinatallyacquiredhiv1infectionaukcrosssectionalobservationalstudy
AT hallrebecca outcomesoffertilityinvestigationsinacohortofadultswithperinatallyacquiredhiv1infectionaukcrosssectionalobservationalstudy
AT petersenclaire outcomesoffertilityinvestigationsinacohortofadultswithperinatallyacquiredhiv1infectionaukcrosssectionalobservationalstudy
AT khanmaryam outcomesoffertilityinvestigationsinacohortofadultswithperinatallyacquiredhiv1infectionaukcrosssectionalobservationalstudy
AT ayressara outcomesoffertilityinvestigationsinacohortofadultswithperinatallyacquiredhiv1infectionaukcrosssectionalobservationalstudy
AT jayasenachannan outcomesoffertilityinvestigationsinacohortofadultswithperinatallyacquiredhiv1infectionaukcrosssectionalobservationalstudy
AT fostercaroline outcomesoffertilityinvestigationsinacohortofadultswithperinatallyacquiredhiv1infectionaukcrosssectionalobservationalstudy
AT fidlersarah outcomesoffertilityinvestigationsinacohortofadultswithperinatallyacquiredhiv1infectionaukcrosssectionalobservationalstudy