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Impact of Dose Reduction on Efficacy: Implications of Exposure-Response Analysis of Palbociclib

BACKGROUND: Palbociclib is indicated for hormone receptor–positive, human epidermal growth factor receptor 2–negative advanced breast cancer (ABC). OBJECTIVE: Exposure-response analyses were conducted to evaluate efficacy in Asian versus non-Asian patients and in patients with versus without dose re...

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Detalles Bibliográficos
Autores principales: Zheng, Jenny, Yu, Yanke, Durairaj, Chandrasekar, Diéras, Véronique, Finn, Richard S., Wang, Diane D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810610/
https://www.ncbi.nlm.nih.gov/pubmed/33211314
http://dx.doi.org/10.1007/s11523-020-00771-5