Sarcolipin alters SERCA1a interdomain communication by impairing binding of both calcium and ATP

Sarcolipin (SLN), a single-spanning membrane protein, is a regulator of the sarco-endoplasmic reticulum Ca(2+)-ATPase (SERCA1a). Chemically synthesized SLN, palmitoylated or not (pSLN or SLN), and recombinant wild-type rabbit SERCA1a expressed in S. cerevisiae design experimental conditions that pro...

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Detalles Bibliográficos
Autores principales: Montigny, Cédric, Huang, Dong Liang, Beswick, Veronica, Barbot, Thomas, Jaxel, Christine, le Maire, Marc, Zheng, Ji-Shen, Jamin, Nadège
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810697/
https://www.ncbi.nlm.nih.gov/pubmed/33452371
http://dx.doi.org/10.1038/s41598-021-81061-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810697/
https://www.ncbi.nlm.nih.gov/pubmed/33452371
http://dx.doi.org/10.1038/s41598-021-81061-6

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