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Vulnerability to shear stress caused by altered peri-endothelial matrix is a key feature of Moyamoya disease
Moyamoya disease (MMD) is characterized by progressive bilateral stenotic changes in the terminal portion of the internal carotid arteries. Although RNF213 was identified as a susceptibility gene for MMD, the exact pathogenesis remains unknown. Immunohistochemical analysis of autopsy specimens from...
Autores principales: | Matsuo, Muneaki, Nadanaka, Satomi, Soga, Minami, Sugiyama, Taku, Serigano, Shota, Shimano, Kenjiro, Ichinose, Fumio, Nakamura, Takuji, Maeda, Toshiyuki, Houkin, Kiyohiro, Era, Takumi, Kitagawa, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810726/ https://www.ncbi.nlm.nih.gov/pubmed/33452387 http://dx.doi.org/10.1038/s41598-021-81282-9 |
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