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Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure

To determine whether state-of-the-art multi-energy spectral photon-counting computed tomography (MARS) can detect knee arthroplasty implant failure not detected by standard pre-operative imaging techniques. A total knee arthroplasty (TKA) removed from a patient was reviewed. The extracted prosthesis...

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Autores principales: Lau, Lawrence Chun Man, Lee, Wayne Yuk Wai, Butler, Anthony P. H., Chernoglazov, Alex I., Chung, Kwong Yin, Ho, Kevin Ki Wai, Griffith, James, Butler, Philip H., Yung, Patrick Shu Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810731/
https://www.ncbi.nlm.nih.gov/pubmed/33452309
http://dx.doi.org/10.1038/s41598-020-80463-2
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author Lau, Lawrence Chun Man
Lee, Wayne Yuk Wai
Butler, Anthony P. H.
Chernoglazov, Alex I.
Chung, Kwong Yin
Ho, Kevin Ki Wai
Griffith, James
Butler, Philip H.
Yung, Patrick Shu Hang
author_facet Lau, Lawrence Chun Man
Lee, Wayne Yuk Wai
Butler, Anthony P. H.
Chernoglazov, Alex I.
Chung, Kwong Yin
Ho, Kevin Ki Wai
Griffith, James
Butler, Philip H.
Yung, Patrick Shu Hang
author_sort Lau, Lawrence Chun Man
collection PubMed
description To determine whether state-of-the-art multi-energy spectral photon-counting computed tomography (MARS) can detect knee arthroplasty implant failure not detected by standard pre-operative imaging techniques. A total knee arthroplasty (TKA) removed from a patient was reviewed. The extracted prosthesis [NexGen Legacy Posterior Stabilized (LPS) TKA] was analyzed as were pre-operative imaging examination and compared with a MARS-CT examination obtained of the extracted TKA prosthesis. Radiographs, fluoroscopy, ultrasound and MRI preoperatively did not reveal the cause of the implant failure. MARS CT images of the extracted prosthesis clearly showed the presence of posteromedial polyethylene and tibial tray wear which is compatible with the clinical appearance of the extracted TKA. MARS can identify polyethylene insert and metallic tibial tray wear as a cause of TKA failure, that could not be identified with on standard pre-operative imaging. Although clinical MARS CT system is still under development, this case does illustrate its potential clinical usefulness. This is the first study to document how MARS CT imaging can detect orthopedic implant failure not detected by standard current imaging techniques. This system has a potential clinical application in orthopedic patients.
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spelling pubmed-78107312021-01-21 Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure Lau, Lawrence Chun Man Lee, Wayne Yuk Wai Butler, Anthony P. H. Chernoglazov, Alex I. Chung, Kwong Yin Ho, Kevin Ki Wai Griffith, James Butler, Philip H. Yung, Patrick Shu Hang Sci Rep Article To determine whether state-of-the-art multi-energy spectral photon-counting computed tomography (MARS) can detect knee arthroplasty implant failure not detected by standard pre-operative imaging techniques. A total knee arthroplasty (TKA) removed from a patient was reviewed. The extracted prosthesis [NexGen Legacy Posterior Stabilized (LPS) TKA] was analyzed as were pre-operative imaging examination and compared with a MARS-CT examination obtained of the extracted TKA prosthesis. Radiographs, fluoroscopy, ultrasound and MRI preoperatively did not reveal the cause of the implant failure. MARS CT images of the extracted prosthesis clearly showed the presence of posteromedial polyethylene and tibial tray wear which is compatible with the clinical appearance of the extracted TKA. MARS can identify polyethylene insert and metallic tibial tray wear as a cause of TKA failure, that could not be identified with on standard pre-operative imaging. Although clinical MARS CT system is still under development, this case does illustrate its potential clinical usefulness. This is the first study to document how MARS CT imaging can detect orthopedic implant failure not detected by standard current imaging techniques. This system has a potential clinical application in orthopedic patients. Nature Publishing Group UK 2021-01-15 /pmc/articles/PMC7810731/ /pubmed/33452309 http://dx.doi.org/10.1038/s41598-020-80463-2 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Lau, Lawrence Chun Man
Lee, Wayne Yuk Wai
Butler, Anthony P. H.
Chernoglazov, Alex I.
Chung, Kwong Yin
Ho, Kevin Ki Wai
Griffith, James
Butler, Philip H.
Yung, Patrick Shu Hang
Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_full Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_fullStr Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_full_unstemmed Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_short Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_sort multi-energy spectral photon-counting computed tomography (mars) for detection of arthroplasty implant failure
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810731/
https://www.ncbi.nlm.nih.gov/pubmed/33452309
http://dx.doi.org/10.1038/s41598-020-80463-2
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