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A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation

To explore the predictive performance of machine learning on the recurrence of patients with gastric cancer after the operation. The available data is divided into two parts. In particular, the first part is used as a training set (such as 80% of the original data), and the second part is used as a...

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Autores principales: Zhou, Chengmao, Hu, Junhong, Wang, Ying, Ji, Mu-Huo, Tong, Jianhua, Yang, Jian-Jun, Xia, Hongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810757/
https://www.ncbi.nlm.nih.gov/pubmed/33452440
http://dx.doi.org/10.1038/s41598-021-81188-6
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author Zhou, Chengmao
Hu, Junhong
Wang, Ying
Ji, Mu-Huo
Tong, Jianhua
Yang, Jian-Jun
Xia, Hongping
author_facet Zhou, Chengmao
Hu, Junhong
Wang, Ying
Ji, Mu-Huo
Tong, Jianhua
Yang, Jian-Jun
Xia, Hongping
author_sort Zhou, Chengmao
collection PubMed
description To explore the predictive performance of machine learning on the recurrence of patients with gastric cancer after the operation. The available data is divided into two parts. In particular, the first part is used as a training set (such as 80% of the original data), and the second part is used as a test set (the remaining 20% of the data). And we use fivefold cross-validation. The weight of recurrence factors shows the top four factors are BMI, Operation time, WGT and age in order. In training group:among the 5 machine learning models, the accuracy of gbm was 0.891, followed by gbm algorithm was 0.876; The AUC values of the five machine learning algorithms are from high to low as forest (0.962), gbm (0.922), GradientBoosting (0.898), DecisionTree (0.790) and Logistic (0.748). And the precision of the forest is the highest 0.957, followed by the GradientBoosting algorithm (0.878). At the same time, in the test group is as follows: the highest accuracy of Logistic was 0.801, followed by forest algorithm and gbm; the AUC values of the five algorithms are forest (0.795), GradientBoosting (0.774), DecisionTree (0.773), Logistic (0.771) and gbm (0.771), from high to low. Among the five machine learning algorithms, the highest precision rate of Logistic is 1.000, followed by the gbm (0.487). Machine learning can predict the recurrence of gastric cancer patients after an operation. Besides, the first four factors affecting postoperative recurrence of gastric cancer were BMI, Operation time, WGT and age.
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spelling pubmed-78107572021-01-21 A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation Zhou, Chengmao Hu, Junhong Wang, Ying Ji, Mu-Huo Tong, Jianhua Yang, Jian-Jun Xia, Hongping Sci Rep Article To explore the predictive performance of machine learning on the recurrence of patients with gastric cancer after the operation. The available data is divided into two parts. In particular, the first part is used as a training set (such as 80% of the original data), and the second part is used as a test set (the remaining 20% of the data). And we use fivefold cross-validation. The weight of recurrence factors shows the top four factors are BMI, Operation time, WGT and age in order. In training group:among the 5 machine learning models, the accuracy of gbm was 0.891, followed by gbm algorithm was 0.876; The AUC values of the five machine learning algorithms are from high to low as forest (0.962), gbm (0.922), GradientBoosting (0.898), DecisionTree (0.790) and Logistic (0.748). And the precision of the forest is the highest 0.957, followed by the GradientBoosting algorithm (0.878). At the same time, in the test group is as follows: the highest accuracy of Logistic was 0.801, followed by forest algorithm and gbm; the AUC values of the five algorithms are forest (0.795), GradientBoosting (0.774), DecisionTree (0.773), Logistic (0.771) and gbm (0.771), from high to low. Among the five machine learning algorithms, the highest precision rate of Logistic is 1.000, followed by the gbm (0.487). Machine learning can predict the recurrence of gastric cancer patients after an operation. Besides, the first four factors affecting postoperative recurrence of gastric cancer were BMI, Operation time, WGT and age. Nature Publishing Group UK 2021-01-15 /pmc/articles/PMC7810757/ /pubmed/33452440 http://dx.doi.org/10.1038/s41598-021-81188-6 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Zhou, Chengmao
Hu, Junhong
Wang, Ying
Ji, Mu-Huo
Tong, Jianhua
Yang, Jian-Jun
Xia, Hongping
A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation
title A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation
title_full A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation
title_fullStr A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation
title_full_unstemmed A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation
title_short A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation
title_sort machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810757/
https://www.ncbi.nlm.nih.gov/pubmed/33452440
http://dx.doi.org/10.1038/s41598-021-81188-6
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