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A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation
To explore the predictive performance of machine learning on the recurrence of patients with gastric cancer after the operation. The available data is divided into two parts. In particular, the first part is used as a training set (such as 80% of the original data), and the second part is used as a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810757/ https://www.ncbi.nlm.nih.gov/pubmed/33452440 http://dx.doi.org/10.1038/s41598-021-81188-6 |
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author | Zhou, Chengmao Hu, Junhong Wang, Ying Ji, Mu-Huo Tong, Jianhua Yang, Jian-Jun Xia, Hongping |
author_facet | Zhou, Chengmao Hu, Junhong Wang, Ying Ji, Mu-Huo Tong, Jianhua Yang, Jian-Jun Xia, Hongping |
author_sort | Zhou, Chengmao |
collection | PubMed |
description | To explore the predictive performance of machine learning on the recurrence of patients with gastric cancer after the operation. The available data is divided into two parts. In particular, the first part is used as a training set (such as 80% of the original data), and the second part is used as a test set (the remaining 20% of the data). And we use fivefold cross-validation. The weight of recurrence factors shows the top four factors are BMI, Operation time, WGT and age in order. In training group:among the 5 machine learning models, the accuracy of gbm was 0.891, followed by gbm algorithm was 0.876; The AUC values of the five machine learning algorithms are from high to low as forest (0.962), gbm (0.922), GradientBoosting (0.898), DecisionTree (0.790) and Logistic (0.748). And the precision of the forest is the highest 0.957, followed by the GradientBoosting algorithm (0.878). At the same time, in the test group is as follows: the highest accuracy of Logistic was 0.801, followed by forest algorithm and gbm; the AUC values of the five algorithms are forest (0.795), GradientBoosting (0.774), DecisionTree (0.773), Logistic (0.771) and gbm (0.771), from high to low. Among the five machine learning algorithms, the highest precision rate of Logistic is 1.000, followed by the gbm (0.487). Machine learning can predict the recurrence of gastric cancer patients after an operation. Besides, the first four factors affecting postoperative recurrence of gastric cancer were BMI, Operation time, WGT and age. |
format | Online Article Text |
id | pubmed-7810757 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-78107572021-01-21 A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation Zhou, Chengmao Hu, Junhong Wang, Ying Ji, Mu-Huo Tong, Jianhua Yang, Jian-Jun Xia, Hongping Sci Rep Article To explore the predictive performance of machine learning on the recurrence of patients with gastric cancer after the operation. The available data is divided into two parts. In particular, the first part is used as a training set (such as 80% of the original data), and the second part is used as a test set (the remaining 20% of the data). And we use fivefold cross-validation. The weight of recurrence factors shows the top four factors are BMI, Operation time, WGT and age in order. In training group:among the 5 machine learning models, the accuracy of gbm was 0.891, followed by gbm algorithm was 0.876; The AUC values of the five machine learning algorithms are from high to low as forest (0.962), gbm (0.922), GradientBoosting (0.898), DecisionTree (0.790) and Logistic (0.748). And the precision of the forest is the highest 0.957, followed by the GradientBoosting algorithm (0.878). At the same time, in the test group is as follows: the highest accuracy of Logistic was 0.801, followed by forest algorithm and gbm; the AUC values of the five algorithms are forest (0.795), GradientBoosting (0.774), DecisionTree (0.773), Logistic (0.771) and gbm (0.771), from high to low. Among the five machine learning algorithms, the highest precision rate of Logistic is 1.000, followed by the gbm (0.487). Machine learning can predict the recurrence of gastric cancer patients after an operation. Besides, the first four factors affecting postoperative recurrence of gastric cancer were BMI, Operation time, WGT and age. Nature Publishing Group UK 2021-01-15 /pmc/articles/PMC7810757/ /pubmed/33452440 http://dx.doi.org/10.1038/s41598-021-81188-6 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Zhou, Chengmao Hu, Junhong Wang, Ying Ji, Mu-Huo Tong, Jianhua Yang, Jian-Jun Xia, Hongping A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation |
title | A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation |
title_full | A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation |
title_fullStr | A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation |
title_full_unstemmed | A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation |
title_short | A machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation |
title_sort | machine learning-based predictor for the identification of the recurrence of patients with gastric cancer after operation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810757/ https://www.ncbi.nlm.nih.gov/pubmed/33452440 http://dx.doi.org/10.1038/s41598-021-81188-6 |
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