Multimarker scores of Th1 and Th2 immune cellular profiles in peripheral blood predict response and immune related toxicity with CTLA4 blockade and IFNα in melanoma

Neoadjuvant therapy with ipilimumab in combination with high dose IFNα was evaluated in patients with locally/regionally advanced melanoma in a previously reported clinical trial [NCT01608594]. In this study, peripheral immune cell profiling was performed in order to investigate the underlying mecha...

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Detalles Bibliográficos
Autores principales: Khunger, Arjun, Sarikonda, Ghanashyam, Tsau, Jennifer, Pahuja, Anil, Alfonso, Zeni, Gao, Jane, Laing, Christian, Vaupel, Christine, Dakappagari, Naveen, Tarhini, Ahmad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810775/
https://www.ncbi.nlm.nih.gov/pubmed/33450703
http://dx.doi.org/10.1016/j.tranon.2021.101014

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