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A quantitative model of cellular decision making in direct neuronal reprogramming
The direct reprogramming of adult skin fibroblasts to neurons is thought to be controlled by a small set of interacting gene regulators. Here, we investigate how the interaction dynamics between these regulating factors coordinate cellular decision making in direct neuronal reprogramming. We put for...
Autores principales: | Merlevede, Adriaan, Legault, Emilie M., Drugge, Viktor, Barker, Roger A., Drouin-Ouellet, Janelle, Olariu, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810861/ https://www.ncbi.nlm.nih.gov/pubmed/33452356 http://dx.doi.org/10.1038/s41598-021-81089-8 |
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