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Possible diverse contribution of coronary risk factors to left ventricular systolic and diastolic cavity sizes

It is generally believed that risk factors damage the coronary arteries, cause myocardial ischemia, and consequently change the shape of the heart. On the other hand, each of the risk factors may also have a negative effect on the heart. However, it is very difficult to examine the effects of each o...

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Autores principales: Suzuki, Kenichiro, Inoue, Yasunori, Ogawa, Kazuo, Nagoshi, Tomohisa, Minai, Kosuke, Ogawa, Takayuki, Kawai, Makoto, Yoshimura, Michihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810980/
https://www.ncbi.nlm.nih.gov/pubmed/33452451
http://dx.doi.org/10.1038/s41598-021-81341-1
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author Suzuki, Kenichiro
Inoue, Yasunori
Ogawa, Kazuo
Nagoshi, Tomohisa
Minai, Kosuke
Ogawa, Takayuki
Kawai, Makoto
Yoshimura, Michihiro
author_facet Suzuki, Kenichiro
Inoue, Yasunori
Ogawa, Kazuo
Nagoshi, Tomohisa
Minai, Kosuke
Ogawa, Takayuki
Kawai, Makoto
Yoshimura, Michihiro
author_sort Suzuki, Kenichiro
collection PubMed
description It is generally believed that risk factors damage the coronary arteries, cause myocardial ischemia, and consequently change the shape of the heart. On the other hand, each of the risk factors may also have a negative effect on the heart. However, it is very difficult to examine the effects of each of these risk factors independently. Therefore, it is necessary to select an appropriate statistical method and apply it efficiently. In this study, the effects of coronary risk factors on left ventricular size and cardiac function were investigated using structure equation modeling (SEM), and were shown as Bayesian SEM-based frequency polygons using selected two-dimensional contours. This study showed that each risk factor directly affected the shape of the heart. Because vascular risk and heart failure risk are likely to evolve at the same time, managing risk factors is very important in reducing the heart failure pandemic.
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spelling pubmed-78109802021-01-21 Possible diverse contribution of coronary risk factors to left ventricular systolic and diastolic cavity sizes Suzuki, Kenichiro Inoue, Yasunori Ogawa, Kazuo Nagoshi, Tomohisa Minai, Kosuke Ogawa, Takayuki Kawai, Makoto Yoshimura, Michihiro Sci Rep Article It is generally believed that risk factors damage the coronary arteries, cause myocardial ischemia, and consequently change the shape of the heart. On the other hand, each of the risk factors may also have a negative effect on the heart. However, it is very difficult to examine the effects of each of these risk factors independently. Therefore, it is necessary to select an appropriate statistical method and apply it efficiently. In this study, the effects of coronary risk factors on left ventricular size and cardiac function were investigated using structure equation modeling (SEM), and were shown as Bayesian SEM-based frequency polygons using selected two-dimensional contours. This study showed that each risk factor directly affected the shape of the heart. Because vascular risk and heart failure risk are likely to evolve at the same time, managing risk factors is very important in reducing the heart failure pandemic. Nature Publishing Group UK 2021-01-15 /pmc/articles/PMC7810980/ /pubmed/33452451 http://dx.doi.org/10.1038/s41598-021-81341-1 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Suzuki, Kenichiro
Inoue, Yasunori
Ogawa, Kazuo
Nagoshi, Tomohisa
Minai, Kosuke
Ogawa, Takayuki
Kawai, Makoto
Yoshimura, Michihiro
Possible diverse contribution of coronary risk factors to left ventricular systolic and diastolic cavity sizes
title Possible diverse contribution of coronary risk factors to left ventricular systolic and diastolic cavity sizes
title_full Possible diverse contribution of coronary risk factors to left ventricular systolic and diastolic cavity sizes
title_fullStr Possible diverse contribution of coronary risk factors to left ventricular systolic and diastolic cavity sizes
title_full_unstemmed Possible diverse contribution of coronary risk factors to left ventricular systolic and diastolic cavity sizes
title_short Possible diverse contribution of coronary risk factors to left ventricular systolic and diastolic cavity sizes
title_sort possible diverse contribution of coronary risk factors to left ventricular systolic and diastolic cavity sizes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810980/
https://www.ncbi.nlm.nih.gov/pubmed/33452451
http://dx.doi.org/10.1038/s41598-021-81341-1
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