Spatiotemporal in vivo tracking of polyclonal human regulatory T cells (Tregs) reveals a role for innate immune cells in Treg transplant recruitment

Regulatory T cells (Tregs) are emerging as a new cell-based therapy in solid organ transplantation. Adoptive transfer of Tregs has been shown preclinically to protect from graft rejection, and the safety of Treg therapy has been demonstrated in clinical trials. Despite these successes, the in vivo d...

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Detalles Bibliográficos
Autores principales: Jacob, Jacinta, Nadkarni, Suchita, Volpe, Alessia, Peng, Qi, Tung, Sim L., Hannen, Rosalind F., Mohseni, Yasmin R., Scotta, Cristiano, Marelli-Berg, Federica M., Lechler, Robert I., Smyth, Lesley A., Fruhwirth, Gilbert O., Lombardi, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811063/
https://www.ncbi.nlm.nih.gov/pubmed/33511246
http://dx.doi.org/10.1016/j.omtm.2020.12.003

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