3,3'-Diindolylmethane Enhances Tumor Regression After Radiation Through Protecting Normal Cells to Modulate Antitumor Immunity

PURPOSE: Preclinical and clinical data indicate that radiation therapy acts as an immune modifier, having both immune-stimulatory and immunosuppressive effects on the tumor-immune microenvironment (TIME). 3.3’-diindolylmethane (DIM) sensitizes tumor cells to radiation and protects mice from lethal d...

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Detalles Bibliográficos
Autores principales: Li, Lijun, Chen, Renxiang, Lin, Yun-Tien, Humayun, Arslon, Fornace, Albert J., Li, Heng-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Scientific Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811120/
https://www.ncbi.nlm.nih.gov/pubmed/33490731
http://dx.doi.org/10.1016/j.adro.2020.10.014

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