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Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer’s disease mouse model
Alzheimer’s disease is characterized by the deposition of extracellular amyloid-beta (Aβ) plaques. While microglial phagocytosis is a major mechanism through which Aβ is cleared, there is no method for quantitatively assessing Aβ phagocytic capacity of microglia in vivo. Here, we present a flow cyto...
Autores principales: | Lau, Shun-Fat, Wu, Wei, Seo, Heukjin, Fu, Amy K.Y., Ip, Nancy Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811161/ https://www.ncbi.nlm.nih.gov/pubmed/33490981 http://dx.doi.org/10.1016/j.xpro.2020.100265 |
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