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Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer’s disease mouse model

Alzheimer’s disease is characterized by the deposition of extracellular amyloid-beta (Aβ) plaques. While microglial phagocytosis is a major mechanism through which Aβ is cleared, there is no method for quantitatively assessing Aβ phagocytic capacity of microglia in vivo. Here, we present a flow cyto...

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Detalles Bibliográficos
Autores principales: Lau, Shun-Fat, Wu, Wei, Seo, Heukjin, Fu, Amy K.Y., Ip, Nancy Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811161/
https://www.ncbi.nlm.nih.gov/pubmed/33490981
http://dx.doi.org/10.1016/j.xpro.2020.100265

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