Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity

OBJECTIVES: Preferential damage to fast, glycolytic myofibers is common in many muscle-wasting diseases, including Duchenne muscular dystrophy (DMD). Promoting an oxidative phenotype could protect muscles from damage and ameliorate the dystrophic pathology with therapeutic relevance, but developing...

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Detalles Bibliográficos
Autores principales: Hardee, Justin P., Martins, Karen J.B., Miotto, Paula M., Ryall, James G., Gehrig, Stefan M., Reljic, Boris, Naim, Timur, Chung, Jin D., Trieu, Jen, Swiderski, Kristy, Philp, Ashleigh M., Philp, Andrew, Watt, Matthew J., Stroud, David A., Koopman, Rene, Steinberg, Gregory R., Lynch, Gordon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811171/
https://www.ncbi.nlm.nih.gov/pubmed/33359740
http://dx.doi.org/10.1016/j.molmet.2020.101157

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