Off-label intravenous thrombolysis for early recurrent brain embolism associated with aortic arch thrombus

Safety data of intravenous thrombolysis (IVT) in presence of aortic arch thrombus is scant. Furthermore, IVT is debatable in patients with prior recent stroke. We present a 51-year-old woman with recurrent major infarction 5 days after a minor left MCA territory stroke. She had a floating aortic arc...

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Autores principales: Koutroulou, Ioanna, Tsivgoulis, Georgios, Rafailidis, Vasileios, Psoma, Elissavet, Kouskouras, Konstantinos, Fotiadis, Panagiotis, Grigoriadis, Nikolaos, Karapanayiotides, Theodoros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811222/
https://www.ncbi.nlm.nih.gov/pubmed/33499927
http://dx.doi.org/10.1186/s42466-021-00103-6
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author Koutroulou, Ioanna
Tsivgoulis, Georgios
Rafailidis, Vasileios
Psoma, Elissavet
Kouskouras, Konstantinos
Fotiadis, Panagiotis
Grigoriadis, Nikolaos
Karapanayiotides, Theodoros
author_facet Koutroulou, Ioanna
Tsivgoulis, Georgios
Rafailidis, Vasileios
Psoma, Elissavet
Kouskouras, Konstantinos
Fotiadis, Panagiotis
Grigoriadis, Nikolaos
Karapanayiotides, Theodoros
author_sort Koutroulou, Ioanna
collection PubMed
description Safety data of intravenous thrombolysis (IVT) in presence of aortic arch thrombus is scant. Furthermore, IVT is debatable in patients with prior recent stroke. We present a 51-year-old woman with recurrent major infarction 5 days after a minor left MCA territory stroke. She had a floating aortic arch thrombus and she was treated safely and effectively with off-label IVT. Patients with small infarct volumes and mild/no residual neurological deficits after an initial stroke might be considered for IVT in case of early recurrence. IVT may be reasonable in a context of acute severely disabling stroke associated with aortic arch thrombus.
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spelling pubmed-78112222021-04-20 Off-label intravenous thrombolysis for early recurrent brain embolism associated with aortic arch thrombus Koutroulou, Ioanna Tsivgoulis, Georgios Rafailidis, Vasileios Psoma, Elissavet Kouskouras, Konstantinos Fotiadis, Panagiotis Grigoriadis, Nikolaos Karapanayiotides, Theodoros Neurol Res Pract Letter to the Editor Safety data of intravenous thrombolysis (IVT) in presence of aortic arch thrombus is scant. Furthermore, IVT is debatable in patients with prior recent stroke. We present a 51-year-old woman with recurrent major infarction 5 days after a minor left MCA territory stroke. She had a floating aortic arch thrombus and she was treated safely and effectively with off-label IVT. Patients with small infarct volumes and mild/no residual neurological deficits after an initial stroke might be considered for IVT in case of early recurrence. IVT may be reasonable in a context of acute severely disabling stroke associated with aortic arch thrombus. BioMed Central 2021-01-16 /pmc/articles/PMC7811222/ /pubmed/33499927 http://dx.doi.org/10.1186/s42466-021-00103-6 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Letter to the Editor
Koutroulou, Ioanna
Tsivgoulis, Georgios
Rafailidis, Vasileios
Psoma, Elissavet
Kouskouras, Konstantinos
Fotiadis, Panagiotis
Grigoriadis, Nikolaos
Karapanayiotides, Theodoros
Off-label intravenous thrombolysis for early recurrent brain embolism associated with aortic arch thrombus
title Off-label intravenous thrombolysis for early recurrent brain embolism associated with aortic arch thrombus
title_full Off-label intravenous thrombolysis for early recurrent brain embolism associated with aortic arch thrombus
title_fullStr Off-label intravenous thrombolysis for early recurrent brain embolism associated with aortic arch thrombus
title_full_unstemmed Off-label intravenous thrombolysis for early recurrent brain embolism associated with aortic arch thrombus
title_short Off-label intravenous thrombolysis for early recurrent brain embolism associated with aortic arch thrombus
title_sort off-label intravenous thrombolysis for early recurrent brain embolism associated with aortic arch thrombus
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811222/
https://www.ncbi.nlm.nih.gov/pubmed/33499927
http://dx.doi.org/10.1186/s42466-021-00103-6
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