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Post-status epilepticus treatment with the Fyn inhibitor, saracatinib, improves cognitive function in mice
BACKGROUND: Status epilepticus (SE) is a life-threatening neurological disorder. The hippocampus, as an important area of the brain that regulates cognitive function, is usually damaged after SE, and cognitive deficits often result from hippocampal neurons lost after SE. Fyn, a non-receptor Src fami...
Autores principales: | Luo, Xin-Ming, Zhao, Jing, Wu, Wen-Yue, Fu, Jie, Li, Zheng-Yu, Zhang, Ming, Lu, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811255/ https://www.ncbi.nlm.nih.gov/pubmed/33451301 http://dx.doi.org/10.1186/s12868-020-00606-z |
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